Microwave-assisted CAN promoted synthesis of poly-substituted pyridine - Vala, Nileshkumar Dhirubhai
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This book compiles with the microwave-assisted synthesis, characterization and in vitro antimicrobial evaluation of 2,4,6-trisubstituted pyridine derivatives catalyzed by ceric ammonium nitrate (CAN), also the effect of halogen substitution on antimicrobial activities. This synthetic study involves one pot cyclo-condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d and various substituted acetophenone 7a-d under microwave irradiation catalyzed by ceric ammonium nitrate (CAN) to gives 2,4,6-trisubstituted pyridine derivatives 8a-p. So, it is worthy to narrate brief introduction…mehr

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Produktbeschreibung
This book compiles with the microwave-assisted synthesis, characterization and in vitro antimicrobial evaluation of 2,4,6-trisubstituted pyridine derivatives catalyzed by ceric ammonium nitrate (CAN), also the effect of halogen substitution on antimicrobial activities. This synthetic study involves one pot cyclo-condensation reaction of 3-substituted-1H-pyrazole-4-carbaldehyde 1a-d and various substituted acetophenone 7a-d under microwave irradiation catalyzed by ceric ammonium nitrate (CAN) to gives 2,4,6-trisubstituted pyridine derivatives 8a-p. So, it is worthy to narrate brief introduction regarding CAN and synthetic and biological consequence of the 2,4,6-trisubstituted pyridine (polysubstituted pyridine) derivatives.
Autorenporträt
Vala, Nileshkumar Dhirubhai
Dr. Nileshkumar D. Vala has completed his B.Sc Chemistry and M.Sc Analytical Chemistry from Sardar Patel University. Also, his Ph.D. is from the Chemistry Department, Sardar Patel University, Vallabh Vidya Nagar, Gujarat, INDIA. He is expert in the organic synthetic methodology.