Migraine Pain Management

Current Pharmacological and Non-Pharmacological Options
Herausgeber: Shrewsbury, Stephen B

• Broschiertes Buch

Produktbeschreibung

Migraine Management: Current Pharmacological and Non-pharmacological Options is a comprehensive guide to established, recent, and ongoing pharmaceuticals and device development projects. The book provides detailed information on the historical developments of migraine pain management, druggable targets, drugs action mechanisms, drugs for acute treatment and preventive care of patients, administration routes, and alternative treatments. This is the ideal reference for academic researchers interested in anti-migraine pharmacology. It is also the perfect reference for physicians and care professionals involved in the well-being of migraine patients.

Produktdetails

• Verlag: Elsevier Health Sciences
• Seitenzahl: 500
• Erscheinungstermin: 1. November 2024
• Englisch
• ISBN-13: 9780443247057
• ISBN-10: 0443247056
• Artikelnr.: 70891170

Inhaltsangabe

Part I: Foundations and historical development of migraine pain management
1. Introduction
2. Neuroanatomy and Neurophysiology
3. Historical overview of migraine product development
4. Comorbidities and their impact on therapies
5. Not all Migraine attacks are the same
6. Challenges and Controversies; Pharmacokinetics, Linguistics, Semantics
and Statistics
Part II: Druggable targets
7. CGRP
8. PACAP
9. Src family kinases (SFK) in Migraine
10. Delta opioid receptor system
11. Piezo channels in peripheral trigeminal nociception
12. TRP antagonists
Part III: Drugs - Acute Management
13. Simple analgesics and combination oral products
14. Cannabinoids & Phytochemicals
15. Ergots
16. Triptans
17. Beta blocker (timolol) eye drops
18. Lasmiditan (and the ditan class)
19. Gepants
Part IV: Drugs - Prevention
20. TCAs (Tricyclic Antidepresants), SNRIs, Beta blockers, candesartan,
flunarizine
21. Antiseizure orals (gabapentin, topiramate)
22. Onabotulinumtoxin
23. Gepants (for prevention)
24. (CGRP) Monocloncal antibodies
Part V: Administration routes
25. Oral Drugs (including SMEDDS)
26. Inhaled - oral & nasal
27. Subcutaneous/IM/Transcutaneous ("Injectables")
28. IV/Infusion
Part VI: Alternative Management
29. The role of digital platforms and smartphone apps
30. Herbal Medicines
31. Phototherapy
32. Neuromodulation
33. Acupuncture (for episodic and chronic migraine)
34. Manual Therapies
35. Nutraceuticals and Diets
36. Mindfulness
Part VII: Summary & conclusion [Shrewsbury]
37. Final Perspectives: oral/non-oral pharmaceuticals; devices;
Complimentary practices