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Mineral trioxide aggregate (MTA) was developed more than 20 years ago to seal the pathways of communication of the root canal system. It's currently the preferred material used by endodontists because of its superior properties such as its seal and biocompatibility that significantly improves outcomes of endodontic treatments.
Dr. Torabinejad, who was the principle investigator of the dental applications of MTA, and leading authorities on this subject provide a clinically focused reference detailing the properties and uses of MTA, including vital pulp therapy (pulp capping, pulpotomy),…mehr
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Mineral trioxide aggregate (MTA) was developed more than 20 years ago to seal the pathways of communication of the root canal system. It's currently the preferred material used by endodontists because of its superior properties such as its seal and biocompatibility that significantly improves outcomes of endodontic treatments.
Dr. Torabinejad, who was the principle investigator of the dental applications of MTA, and leading authorities on this subject provide a clinically focused reference detailing the properties and uses of MTA, including vital pulp therapy (pulp capping, pulpotomy), apexification, pulp regeneration, repair of root perforations, root end filling and root canal filling. Line illustrations and clinical photographs show proper technique. An accompanying website features photographs and video presentations for selected procedures using MTA.
Mineral Trioxide Aggregate: Properties and Clinical Applications is an ideal book for dental students and endodontic residents learning procedures for the first time as well as practicing dentists and endodontists who would like to improve outcomes of endodontic treatments.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Dr. Torabinejad, who was the principle investigator of the dental applications of MTA, and leading authorities on this subject provide a clinically focused reference detailing the properties and uses of MTA, including vital pulp therapy (pulp capping, pulpotomy), apexification, pulp regeneration, repair of root perforations, root end filling and root canal filling. Line illustrations and clinical photographs show proper technique. An accompanying website features photographs and video presentations for selected procedures using MTA.
Mineral Trioxide Aggregate: Properties and Clinical Applications is an ideal book for dental students and endodontic residents learning procedures for the first time as well as practicing dentists and endodontists who would like to improve outcomes of endodontic treatments.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 360
- Erscheinungstermin: 25. August 2014
- Englisch
- Abmessung: 244mm x 170mm x 20mm
- Gewicht: 1479g
- ISBN-13: 9781118401286
- ISBN-10: 111840128X
- Artikelnr.: 41196120
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 360
- Erscheinungstermin: 25. August 2014
- Englisch
- Abmessung: 244mm x 170mm x 20mm
- Gewicht: 1479g
- ISBN-13: 9781118401286
- ISBN-10: 111840128X
- Artikelnr.: 41196120
Mahmoud Torabinejad, DMD, MSD, PhD, is Professor of Endodontics and Director of the Advanced Specialty Education Program in Endodontics at Loma Linda University School of Dentistry in Loma Linda, California. As a researcher and international lecturer on dental and endodontic issues and procedures, Dr. Torabinejad has made over 200 national and international presentations in more than 40 countries. In addition to co-authoring three textbooks in nonsurgical and surgical endodontics, he has authored more than 300 publications on various endodontic and dental topics. As a researcher, he is the top -cited author in endodontic journals, with authorship in 16 articles of the top 100 list. Dr. Torabinejad was the principle investigator in the applications of MTA in dental procedures.
Contributors xv Preface xvii 1 Pulp and Periradicular Pathways, Pathosis,
and Closure 1 Mahmoud Torabinejad Pulp and Periradicular Pathways 2 Natural
Pathways 2 Apical foramen 2 Lateral canals 4 Dentinal tubules 4
Pathological and Iatrogenic Pathways 5 Dental caries 5 Role of
microorganisms 6 Root perforations 7 Root perforations during access
preparation 7 Root perforations during cleaning and shaping 8 Root
perforations during post space preparations 10 Vertical fracture 10
Periradicular Pathosis 11 Inflammatory process of periradicular lesions 11
Materials to Seal the Pathways to the Root Canal System and the
Periodontium 13 References 15 2 Chemical Properties of MTA 17 David W.
Berzins Introduction 17 MTA Composition 19 Portland cement 19 Role of
bismuth oxide and gypsum 20 MTA powder morphology 21 Trace elements and
compounds 23 Setting Reactions 23 Setting time 26 Maturation 26 Factors
that affect setting: additives and accelerants 26 Effect of water and
moisture 27 Interaction with environment 27 Development of Reaction Zones
28 References 31 3 Physical Properties of MTA 37 Ricardo Caicedo and
Lawrence Gettleman Introduction 38 pH 38 Solubility 40 Setting Expansion 45
Radiopacity 46 Various Types of Strength 49 Compressive strength 49
Flexural strength 54 Shear strength 55 Push-out strength 56 Shear bond
strength 56 Overview 57 Microhardness 59 Color and Aesthetics 61
Physicochemical Properties 62 Acknowledgment 66 References 66 4 MTA in
Vital Pulp Therapy 71 Till Dammaschke, Joe H. Camp, and George Bogen
Introduction 72 Advantages 74 Pulp Responses to Capping Materials 74 Direct
Pulp Capping with Calcium Hydroxide 75 Mineral Trioxide Aggregate 77
Physiochemical properties 77 Mode of action in pulp capping and pulpotomy
80 Comparison with calcium hydroxide 83 Pulpotomy in Primary Teeth 85 MTA
Pulpotomy 86 Primary teeth 86 Immature permanent teeth 88 Symptomatic
permanent teeth 90 Pulp Capping in Teeth Diagnosed with Reversible Pulpitis
94 Treatment Considerations 96 Disadvantages 98 Summary 99 Acknowledgment
99 References 100 5 Management of Teeth with Necrotic Pulps and Open Apices
111 Shahrokh Shabahang and David E. Witherspoon Diagnosis in Immature Teeth
111 History of Treating Immature Teeth 114 Infection Control in Immature
Teeth 116 Apexification 118 Calcium Hydroxide Apexification Therapy:
Outcomes 119 Non-Vital Pulp Therapy 121 Root-end closure via the use of
apical barriers 121 Mineral trioxide aggregate apical plug 122 Technical
placement 124 Outcomes 124 References 131 6 Regenerative Endodontics
(Revitalization/Revascularization) 141 Mahmoud Torabinejad, Robert P. Corr,
and George T.-J. Huang Introduction 142 Revascularization after
Replantation and Autotransplantation 143 Revitalization of
Nonvital-Infected Teeth in Animals 145 Clinical Evidence for Revitalization
in Nonvital-Infected Teeth in Humans 152 Potential Role of Stem Cells in
Canal Tissue Generation and Regeneration 160 Role of DPSCs and SCAP in
revitalization and regenerative endodontic treatments 161 Scaffolds and
growth factors for regenerative endodontics (Revitalization) 164 Clinical
Procedures for Pulp Revitalization 168 First appointment 168 Second
appointment 168 Clinical and radiographic follow-up 170 References 170 7
Use of MTA as Root Perforation Repair 177 Mahmoud Torabinejad and Ron Lemon
Introduction 178 Types of Perforation Defects 182 Access
preparation-related perforations 182 Cleaning and shaping related ("strip")
perforations 184 Resorption-related perforations (internal/external) 184
Factors Influencing Prognosis for Repair 187 Size of perforation 187
Location of the perforation 187 Pulp Chamber Perforations 189 Etiologies
189 Prevention 189 Recognition and treatment of pulp chamber perforations
189 Lateral surface repairs 190 Furcation repairs 190 Root Perforations
During Cleaning and Shaping 191 Coronal root perforations 191 Causes,
indicators and prevention 191 Treatment 193 Prognosis 193 Lateral
perforations 194 Causes and indicators 194 Treatment of mid-root
perforation 194 Prognosis 195 Apical perforations 195 Causes and indicators
196 Treatment 197 Prognosis 197 Root Perforation during Post Space
preparation 197 Causes, indicators and prevention 197 Treatment 197
Prognosis 199 Time elapsed since perforation 199 Techniques for Internal
Repair Using MTA 199 Method 199 Summary 202 References 203 8 MTA Root Canal
Obturation 207 George Bogen, Ingrid Lawaty, and Nicholas Chandler
Introduction 208 Charactertics/Properties 210 Mechanisms of action in
obturation 210 Particle size 211 Hydration products and pH 211 Formation of
interstitial layer 212 Fracture resistance 212 Sealing ability and setting
expansion 213 Applications/Uses 214 Conventional obturation 214 Retreatment
216 Obturation prior to surgery 219 Obturation with perforation repair 219
Apexification using MTA obturation 222 Obturation for dental anomalies 225
Obturation Techniques 225 Standard compaction technique 226 Lawaty
technique 229 Auger technique 231 Restorative Considerations 234 Drawbacks
234 Sealers 235 Zinc oxide-eugenol sealers 236 Calcium hydroxide sealers
236 Epoxy resin-based sealers 236 Glass ionomer sealers 237 Silicone-based
sealers 237 Monoblock sealer systems 237 Calcium silicate-based sealers 237
Summary 238 References 239 9 Root-End Fillings Using MTA 251 Seung-Ho Baek
and Su-Jung Shin Introduction of Root-End Filling Materials 252 Purpose of
root-end fillings 252 History of Root-End Filling Materials 253 Amalgam 254
ZOE-based materials: IRM and SuperEBA 254 Resin-based materials: Retroplast
and Geristore 256 Mineral trioxide aggregate (MTA) 256 Gray vs. White MTA
257 New types of MTA-like cements 257 Requirements of Ideal Root-End
Filling Materials 258 Advantages and disadvantages of MTA as a root-end
filling material 258 Advantages of MTA 258 Disadvantages of MTA 259 MTA as
a Root-End Filling Material 260 Cytotoxicity and biocompatibility 260
Bioactivity 263 Sealability 264 Antibacterial effect 265 Clinical
Applications of MTA 265 Retropreparation and root-end filling 265 Cavity
preparation for MTA root-end filling 265 Mixing procedure 266 Methods for
placement of MTA 266 Clinical outcomes 268 Conclusion 272 References 275 10
Calcium Silicate-Based Cements 281 Masoud Parirokh and Mahmoud Torabinejad
Introduction 284 Portland Cement (PC) 285 Chemical composition 285 Physical
properties 286 Antibacterial activity 287 Sealing ability 288
Biocompatibility 288 Cell culture studies 288 Subcutaneous implantation 288
In vivo investigations 289 Clinical applications 289 Limitations 289
Angelus MTA 291 Chemical composition 291 Physical properties 292
Antibacterial activity 293 Sealing ability 293 Biocompatibility properties
293 Cell structure studies 293 Subcutaneous implantation 294 Intraosseous
implantation 294 In vivo investigations 294 Clinical applications 295
Bioaggregate (BA) 295 Chemical composition 295 Physical properties 296
Antibacterial activity 296 Sealing ability 296 Biocompatibility 296 Cell
culture studies 296 Biodentine (BD) 297 Chemical composition 297 Physical
properties 297 Biocompatibility and clinical applications 297 iRoot 298
Chemical composition 298 Physical properties 298 Biocompatibility 299
Calcium Enriched Mixture (CEM) Cement 299 Chemical composition 299 Physical
properties 300 Antibacterial activities 301 Sealing ability 301
Biocompatibility 301 Cell culture studies 301 Skin test and subcutaneous
implantation 302 Intraosseous implantation 302 In vivo investigations 302
Clinical investigations 303 MTA Fillapex 304 Chemical composition 304
Physical properties 304 Antibacterial activities 305 Biocompatibility 306
Cell culture studies 306 Subcutaneous implantation 306 Endo-CPM 306
Chemical composition 307 Physical properties 307 Antibacterial activity 307
Sealing ability 307 Biocompatibility 307 Cell culture studies 307
Subcutaneous implantation 307 In vivo investigations 308 Cimento
Endodontico Rapido (CER) 308 Chemical composition 308 Physical properties
308 Biocompatibility 308 Subcutaneous implantation 308 Endosequence 309
Chemical composition 309 Physical properties 309 Antibacterial activities
310 Sealing ability 310 Biocompatibility 310 Cell culture studies 310
EndoSequence BC Sealer 310 Chemical composition 311 Physical properties 311
Biocompatibility 311 ProRoot Endo Sealer 311 Chemical composition 311
Physical properties 312 MTA Plus 312 Chemical composition 312 Physical
properties 312 Ortho MTA 313 Chemical composition 313 Biocompatibility 313
Cell culture studies 313 MTA Bio 313 Chemical composition 313 Physical
properties 314 Biocompatibility 314 Cell culture studies 314 Subcutaneous
implantation 315 MTA Sealer (MTAS) 315 Chemical compositions and physical
properties 315 Fluoride-Doped MTA Cement 315 Chemical composition 315
Physical properties 316 Sealing ability 316 Capasio 316 Chemical
composition and physical properties 316 Generex A 317 Chemical composition
and physical properties 317 Biocompatibility 317 Cell culture study 317
Ceramicrete-D 317 Chemical composition and physical properties 317
Nano-Modified MTA (NMTA) 318 Chemical composition and physical properties
318 Light-Cured MTA 318 Chemical composition and physical properties 318
Biocompatibility 319 Subcutaneous implantation 319 Calcium Silicate (CS)
319 Chemical composition and physical properties 319 Endocem 320 Chemical
composition and physical properties 320 Biocompatibility 320 Cell culture
study 320 Other Experimental MTA Lookalike Mixtures 320 Conclusion 320
References 321 Index 333
and Closure 1 Mahmoud Torabinejad Pulp and Periradicular Pathways 2 Natural
Pathways 2 Apical foramen 2 Lateral canals 4 Dentinal tubules 4
Pathological and Iatrogenic Pathways 5 Dental caries 5 Role of
microorganisms 6 Root perforations 7 Root perforations during access
preparation 7 Root perforations during cleaning and shaping 8 Root
perforations during post space preparations 10 Vertical fracture 10
Periradicular Pathosis 11 Inflammatory process of periradicular lesions 11
Materials to Seal the Pathways to the Root Canal System and the
Periodontium 13 References 15 2 Chemical Properties of MTA 17 David W.
Berzins Introduction 17 MTA Composition 19 Portland cement 19 Role of
bismuth oxide and gypsum 20 MTA powder morphology 21 Trace elements and
compounds 23 Setting Reactions 23 Setting time 26 Maturation 26 Factors
that affect setting: additives and accelerants 26 Effect of water and
moisture 27 Interaction with environment 27 Development of Reaction Zones
28 References 31 3 Physical Properties of MTA 37 Ricardo Caicedo and
Lawrence Gettleman Introduction 38 pH 38 Solubility 40 Setting Expansion 45
Radiopacity 46 Various Types of Strength 49 Compressive strength 49
Flexural strength 54 Shear strength 55 Push-out strength 56 Shear bond
strength 56 Overview 57 Microhardness 59 Color and Aesthetics 61
Physicochemical Properties 62 Acknowledgment 66 References 66 4 MTA in
Vital Pulp Therapy 71 Till Dammaschke, Joe H. Camp, and George Bogen
Introduction 72 Advantages 74 Pulp Responses to Capping Materials 74 Direct
Pulp Capping with Calcium Hydroxide 75 Mineral Trioxide Aggregate 77
Physiochemical properties 77 Mode of action in pulp capping and pulpotomy
80 Comparison with calcium hydroxide 83 Pulpotomy in Primary Teeth 85 MTA
Pulpotomy 86 Primary teeth 86 Immature permanent teeth 88 Symptomatic
permanent teeth 90 Pulp Capping in Teeth Diagnosed with Reversible Pulpitis
94 Treatment Considerations 96 Disadvantages 98 Summary 99 Acknowledgment
99 References 100 5 Management of Teeth with Necrotic Pulps and Open Apices
111 Shahrokh Shabahang and David E. Witherspoon Diagnosis in Immature Teeth
111 History of Treating Immature Teeth 114 Infection Control in Immature
Teeth 116 Apexification 118 Calcium Hydroxide Apexification Therapy:
Outcomes 119 Non-Vital Pulp Therapy 121 Root-end closure via the use of
apical barriers 121 Mineral trioxide aggregate apical plug 122 Technical
placement 124 Outcomes 124 References 131 6 Regenerative Endodontics
(Revitalization/Revascularization) 141 Mahmoud Torabinejad, Robert P. Corr,
and George T.-J. Huang Introduction 142 Revascularization after
Replantation and Autotransplantation 143 Revitalization of
Nonvital-Infected Teeth in Animals 145 Clinical Evidence for Revitalization
in Nonvital-Infected Teeth in Humans 152 Potential Role of Stem Cells in
Canal Tissue Generation and Regeneration 160 Role of DPSCs and SCAP in
revitalization and regenerative endodontic treatments 161 Scaffolds and
growth factors for regenerative endodontics (Revitalization) 164 Clinical
Procedures for Pulp Revitalization 168 First appointment 168 Second
appointment 168 Clinical and radiographic follow-up 170 References 170 7
Use of MTA as Root Perforation Repair 177 Mahmoud Torabinejad and Ron Lemon
Introduction 178 Types of Perforation Defects 182 Access
preparation-related perforations 182 Cleaning and shaping related ("strip")
perforations 184 Resorption-related perforations (internal/external) 184
Factors Influencing Prognosis for Repair 187 Size of perforation 187
Location of the perforation 187 Pulp Chamber Perforations 189 Etiologies
189 Prevention 189 Recognition and treatment of pulp chamber perforations
189 Lateral surface repairs 190 Furcation repairs 190 Root Perforations
During Cleaning and Shaping 191 Coronal root perforations 191 Causes,
indicators and prevention 191 Treatment 193 Prognosis 193 Lateral
perforations 194 Causes and indicators 194 Treatment of mid-root
perforation 194 Prognosis 195 Apical perforations 195 Causes and indicators
196 Treatment 197 Prognosis 197 Root Perforation during Post Space
preparation 197 Causes, indicators and prevention 197 Treatment 197
Prognosis 199 Time elapsed since perforation 199 Techniques for Internal
Repair Using MTA 199 Method 199 Summary 202 References 203 8 MTA Root Canal
Obturation 207 George Bogen, Ingrid Lawaty, and Nicholas Chandler
Introduction 208 Charactertics/Properties 210 Mechanisms of action in
obturation 210 Particle size 211 Hydration products and pH 211 Formation of
interstitial layer 212 Fracture resistance 212 Sealing ability and setting
expansion 213 Applications/Uses 214 Conventional obturation 214 Retreatment
216 Obturation prior to surgery 219 Obturation with perforation repair 219
Apexification using MTA obturation 222 Obturation for dental anomalies 225
Obturation Techniques 225 Standard compaction technique 226 Lawaty
technique 229 Auger technique 231 Restorative Considerations 234 Drawbacks
234 Sealers 235 Zinc oxide-eugenol sealers 236 Calcium hydroxide sealers
236 Epoxy resin-based sealers 236 Glass ionomer sealers 237 Silicone-based
sealers 237 Monoblock sealer systems 237 Calcium silicate-based sealers 237
Summary 238 References 239 9 Root-End Fillings Using MTA 251 Seung-Ho Baek
and Su-Jung Shin Introduction of Root-End Filling Materials 252 Purpose of
root-end fillings 252 History of Root-End Filling Materials 253 Amalgam 254
ZOE-based materials: IRM and SuperEBA 254 Resin-based materials: Retroplast
and Geristore 256 Mineral trioxide aggregate (MTA) 256 Gray vs. White MTA
257 New types of MTA-like cements 257 Requirements of Ideal Root-End
Filling Materials 258 Advantages and disadvantages of MTA as a root-end
filling material 258 Advantages of MTA 258 Disadvantages of MTA 259 MTA as
a Root-End Filling Material 260 Cytotoxicity and biocompatibility 260
Bioactivity 263 Sealability 264 Antibacterial effect 265 Clinical
Applications of MTA 265 Retropreparation and root-end filling 265 Cavity
preparation for MTA root-end filling 265 Mixing procedure 266 Methods for
placement of MTA 266 Clinical outcomes 268 Conclusion 272 References 275 10
Calcium Silicate-Based Cements 281 Masoud Parirokh and Mahmoud Torabinejad
Introduction 284 Portland Cement (PC) 285 Chemical composition 285 Physical
properties 286 Antibacterial activity 287 Sealing ability 288
Biocompatibility 288 Cell culture studies 288 Subcutaneous implantation 288
In vivo investigations 289 Clinical applications 289 Limitations 289
Angelus MTA 291 Chemical composition 291 Physical properties 292
Antibacterial activity 293 Sealing ability 293 Biocompatibility properties
293 Cell structure studies 293 Subcutaneous implantation 294 Intraosseous
implantation 294 In vivo investigations 294 Clinical applications 295
Bioaggregate (BA) 295 Chemical composition 295 Physical properties 296
Antibacterial activity 296 Sealing ability 296 Biocompatibility 296 Cell
culture studies 296 Biodentine (BD) 297 Chemical composition 297 Physical
properties 297 Biocompatibility and clinical applications 297 iRoot 298
Chemical composition 298 Physical properties 298 Biocompatibility 299
Calcium Enriched Mixture (CEM) Cement 299 Chemical composition 299 Physical
properties 300 Antibacterial activities 301 Sealing ability 301
Biocompatibility 301 Cell culture studies 301 Skin test and subcutaneous
implantation 302 Intraosseous implantation 302 In vivo investigations 302
Clinical investigations 303 MTA Fillapex 304 Chemical composition 304
Physical properties 304 Antibacterial activities 305 Biocompatibility 306
Cell culture studies 306 Subcutaneous implantation 306 Endo-CPM 306
Chemical composition 307 Physical properties 307 Antibacterial activity 307
Sealing ability 307 Biocompatibility 307 Cell culture studies 307
Subcutaneous implantation 307 In vivo investigations 308 Cimento
Endodontico Rapido (CER) 308 Chemical composition 308 Physical properties
308 Biocompatibility 308 Subcutaneous implantation 308 Endosequence 309
Chemical composition 309 Physical properties 309 Antibacterial activities
310 Sealing ability 310 Biocompatibility 310 Cell culture studies 310
EndoSequence BC Sealer 310 Chemical composition 311 Physical properties 311
Biocompatibility 311 ProRoot Endo Sealer 311 Chemical composition 311
Physical properties 312 MTA Plus 312 Chemical composition 312 Physical
properties 312 Ortho MTA 313 Chemical composition 313 Biocompatibility 313
Cell culture studies 313 MTA Bio 313 Chemical composition 313 Physical
properties 314 Biocompatibility 314 Cell culture studies 314 Subcutaneous
implantation 315 MTA Sealer (MTAS) 315 Chemical compositions and physical
properties 315 Fluoride-Doped MTA Cement 315 Chemical composition 315
Physical properties 316 Sealing ability 316 Capasio 316 Chemical
composition and physical properties 316 Generex A 317 Chemical composition
and physical properties 317 Biocompatibility 317 Cell culture study 317
Ceramicrete-D 317 Chemical composition and physical properties 317
Nano-Modified MTA (NMTA) 318 Chemical composition and physical properties
318 Light-Cured MTA 318 Chemical composition and physical properties 318
Biocompatibility 319 Subcutaneous implantation 319 Calcium Silicate (CS)
319 Chemical composition and physical properties 319 Endocem 320 Chemical
composition and physical properties 320 Biocompatibility 320 Cell culture
study 320 Other Experimental MTA Lookalike Mixtures 320 Conclusion 320
References 321 Index 333
Contributors xv Preface xvii 1 Pulp and Periradicular Pathways, Pathosis,
and Closure 1 Mahmoud Torabinejad Pulp and Periradicular Pathways 2 Natural
Pathways 2 Apical foramen 2 Lateral canals 4 Dentinal tubules 4
Pathological and Iatrogenic Pathways 5 Dental caries 5 Role of
microorganisms 6 Root perforations 7 Root perforations during access
preparation 7 Root perforations during cleaning and shaping 8 Root
perforations during post space preparations 10 Vertical fracture 10
Periradicular Pathosis 11 Inflammatory process of periradicular lesions 11
Materials to Seal the Pathways to the Root Canal System and the
Periodontium 13 References 15 2 Chemical Properties of MTA 17 David W.
Berzins Introduction 17 MTA Composition 19 Portland cement 19 Role of
bismuth oxide and gypsum 20 MTA powder morphology 21 Trace elements and
compounds 23 Setting Reactions 23 Setting time 26 Maturation 26 Factors
that affect setting: additives and accelerants 26 Effect of water and
moisture 27 Interaction with environment 27 Development of Reaction Zones
28 References 31 3 Physical Properties of MTA 37 Ricardo Caicedo and
Lawrence Gettleman Introduction 38 pH 38 Solubility 40 Setting Expansion 45
Radiopacity 46 Various Types of Strength 49 Compressive strength 49
Flexural strength 54 Shear strength 55 Push-out strength 56 Shear bond
strength 56 Overview 57 Microhardness 59 Color and Aesthetics 61
Physicochemical Properties 62 Acknowledgment 66 References 66 4 MTA in
Vital Pulp Therapy 71 Till Dammaschke, Joe H. Camp, and George Bogen
Introduction 72 Advantages 74 Pulp Responses to Capping Materials 74 Direct
Pulp Capping with Calcium Hydroxide 75 Mineral Trioxide Aggregate 77
Physiochemical properties 77 Mode of action in pulp capping and pulpotomy
80 Comparison with calcium hydroxide 83 Pulpotomy in Primary Teeth 85 MTA
Pulpotomy 86 Primary teeth 86 Immature permanent teeth 88 Symptomatic
permanent teeth 90 Pulp Capping in Teeth Diagnosed with Reversible Pulpitis
94 Treatment Considerations 96 Disadvantages 98 Summary 99 Acknowledgment
99 References 100 5 Management of Teeth with Necrotic Pulps and Open Apices
111 Shahrokh Shabahang and David E. Witherspoon Diagnosis in Immature Teeth
111 History of Treating Immature Teeth 114 Infection Control in Immature
Teeth 116 Apexification 118 Calcium Hydroxide Apexification Therapy:
Outcomes 119 Non-Vital Pulp Therapy 121 Root-end closure via the use of
apical barriers 121 Mineral trioxide aggregate apical plug 122 Technical
placement 124 Outcomes 124 References 131 6 Regenerative Endodontics
(Revitalization/Revascularization) 141 Mahmoud Torabinejad, Robert P. Corr,
and George T.-J. Huang Introduction 142 Revascularization after
Replantation and Autotransplantation 143 Revitalization of
Nonvital-Infected Teeth in Animals 145 Clinical Evidence for Revitalization
in Nonvital-Infected Teeth in Humans 152 Potential Role of Stem Cells in
Canal Tissue Generation and Regeneration 160 Role of DPSCs and SCAP in
revitalization and regenerative endodontic treatments 161 Scaffolds and
growth factors for regenerative endodontics (Revitalization) 164 Clinical
Procedures for Pulp Revitalization 168 First appointment 168 Second
appointment 168 Clinical and radiographic follow-up 170 References 170 7
Use of MTA as Root Perforation Repair 177 Mahmoud Torabinejad and Ron Lemon
Introduction 178 Types of Perforation Defects 182 Access
preparation-related perforations 182 Cleaning and shaping related ("strip")
perforations 184 Resorption-related perforations (internal/external) 184
Factors Influencing Prognosis for Repair 187 Size of perforation 187
Location of the perforation 187 Pulp Chamber Perforations 189 Etiologies
189 Prevention 189 Recognition and treatment of pulp chamber perforations
189 Lateral surface repairs 190 Furcation repairs 190 Root Perforations
During Cleaning and Shaping 191 Coronal root perforations 191 Causes,
indicators and prevention 191 Treatment 193 Prognosis 193 Lateral
perforations 194 Causes and indicators 194 Treatment of mid-root
perforation 194 Prognosis 195 Apical perforations 195 Causes and indicators
196 Treatment 197 Prognosis 197 Root Perforation during Post Space
preparation 197 Causes, indicators and prevention 197 Treatment 197
Prognosis 199 Time elapsed since perforation 199 Techniques for Internal
Repair Using MTA 199 Method 199 Summary 202 References 203 8 MTA Root Canal
Obturation 207 George Bogen, Ingrid Lawaty, and Nicholas Chandler
Introduction 208 Charactertics/Properties 210 Mechanisms of action in
obturation 210 Particle size 211 Hydration products and pH 211 Formation of
interstitial layer 212 Fracture resistance 212 Sealing ability and setting
expansion 213 Applications/Uses 214 Conventional obturation 214 Retreatment
216 Obturation prior to surgery 219 Obturation with perforation repair 219
Apexification using MTA obturation 222 Obturation for dental anomalies 225
Obturation Techniques 225 Standard compaction technique 226 Lawaty
technique 229 Auger technique 231 Restorative Considerations 234 Drawbacks
234 Sealers 235 Zinc oxide-eugenol sealers 236 Calcium hydroxide sealers
236 Epoxy resin-based sealers 236 Glass ionomer sealers 237 Silicone-based
sealers 237 Monoblock sealer systems 237 Calcium silicate-based sealers 237
Summary 238 References 239 9 Root-End Fillings Using MTA 251 Seung-Ho Baek
and Su-Jung Shin Introduction of Root-End Filling Materials 252 Purpose of
root-end fillings 252 History of Root-End Filling Materials 253 Amalgam 254
ZOE-based materials: IRM and SuperEBA 254 Resin-based materials: Retroplast
and Geristore 256 Mineral trioxide aggregate (MTA) 256 Gray vs. White MTA
257 New types of MTA-like cements 257 Requirements of Ideal Root-End
Filling Materials 258 Advantages and disadvantages of MTA as a root-end
filling material 258 Advantages of MTA 258 Disadvantages of MTA 259 MTA as
a Root-End Filling Material 260 Cytotoxicity and biocompatibility 260
Bioactivity 263 Sealability 264 Antibacterial effect 265 Clinical
Applications of MTA 265 Retropreparation and root-end filling 265 Cavity
preparation for MTA root-end filling 265 Mixing procedure 266 Methods for
placement of MTA 266 Clinical outcomes 268 Conclusion 272 References 275 10
Calcium Silicate-Based Cements 281 Masoud Parirokh and Mahmoud Torabinejad
Introduction 284 Portland Cement (PC) 285 Chemical composition 285 Physical
properties 286 Antibacterial activity 287 Sealing ability 288
Biocompatibility 288 Cell culture studies 288 Subcutaneous implantation 288
In vivo investigations 289 Clinical applications 289 Limitations 289
Angelus MTA 291 Chemical composition 291 Physical properties 292
Antibacterial activity 293 Sealing ability 293 Biocompatibility properties
293 Cell structure studies 293 Subcutaneous implantation 294 Intraosseous
implantation 294 In vivo investigations 294 Clinical applications 295
Bioaggregate (BA) 295 Chemical composition 295 Physical properties 296
Antibacterial activity 296 Sealing ability 296 Biocompatibility 296 Cell
culture studies 296 Biodentine (BD) 297 Chemical composition 297 Physical
properties 297 Biocompatibility and clinical applications 297 iRoot 298
Chemical composition 298 Physical properties 298 Biocompatibility 299
Calcium Enriched Mixture (CEM) Cement 299 Chemical composition 299 Physical
properties 300 Antibacterial activities 301 Sealing ability 301
Biocompatibility 301 Cell culture studies 301 Skin test and subcutaneous
implantation 302 Intraosseous implantation 302 In vivo investigations 302
Clinical investigations 303 MTA Fillapex 304 Chemical composition 304
Physical properties 304 Antibacterial activities 305 Biocompatibility 306
Cell culture studies 306 Subcutaneous implantation 306 Endo-CPM 306
Chemical composition 307 Physical properties 307 Antibacterial activity 307
Sealing ability 307 Biocompatibility 307 Cell culture studies 307
Subcutaneous implantation 307 In vivo investigations 308 Cimento
Endodontico Rapido (CER) 308 Chemical composition 308 Physical properties
308 Biocompatibility 308 Subcutaneous implantation 308 Endosequence 309
Chemical composition 309 Physical properties 309 Antibacterial activities
310 Sealing ability 310 Biocompatibility 310 Cell culture studies 310
EndoSequence BC Sealer 310 Chemical composition 311 Physical properties 311
Biocompatibility 311 ProRoot Endo Sealer 311 Chemical composition 311
Physical properties 312 MTA Plus 312 Chemical composition 312 Physical
properties 312 Ortho MTA 313 Chemical composition 313 Biocompatibility 313
Cell culture studies 313 MTA Bio 313 Chemical composition 313 Physical
properties 314 Biocompatibility 314 Cell culture studies 314 Subcutaneous
implantation 315 MTA Sealer (MTAS) 315 Chemical compositions and physical
properties 315 Fluoride-Doped MTA Cement 315 Chemical composition 315
Physical properties 316 Sealing ability 316 Capasio 316 Chemical
composition and physical properties 316 Generex A 317 Chemical composition
and physical properties 317 Biocompatibility 317 Cell culture study 317
Ceramicrete-D 317 Chemical composition and physical properties 317
Nano-Modified MTA (NMTA) 318 Chemical composition and physical properties
318 Light-Cured MTA 318 Chemical composition and physical properties 318
Biocompatibility 319 Subcutaneous implantation 319 Calcium Silicate (CS)
319 Chemical composition and physical properties 319 Endocem 320 Chemical
composition and physical properties 320 Biocompatibility 320 Cell culture
study 320 Other Experimental MTA Lookalike Mixtures 320 Conclusion 320
References 321 Index 333
and Closure 1 Mahmoud Torabinejad Pulp and Periradicular Pathways 2 Natural
Pathways 2 Apical foramen 2 Lateral canals 4 Dentinal tubules 4
Pathological and Iatrogenic Pathways 5 Dental caries 5 Role of
microorganisms 6 Root perforations 7 Root perforations during access
preparation 7 Root perforations during cleaning and shaping 8 Root
perforations during post space preparations 10 Vertical fracture 10
Periradicular Pathosis 11 Inflammatory process of periradicular lesions 11
Materials to Seal the Pathways to the Root Canal System and the
Periodontium 13 References 15 2 Chemical Properties of MTA 17 David W.
Berzins Introduction 17 MTA Composition 19 Portland cement 19 Role of
bismuth oxide and gypsum 20 MTA powder morphology 21 Trace elements and
compounds 23 Setting Reactions 23 Setting time 26 Maturation 26 Factors
that affect setting: additives and accelerants 26 Effect of water and
moisture 27 Interaction with environment 27 Development of Reaction Zones
28 References 31 3 Physical Properties of MTA 37 Ricardo Caicedo and
Lawrence Gettleman Introduction 38 pH 38 Solubility 40 Setting Expansion 45
Radiopacity 46 Various Types of Strength 49 Compressive strength 49
Flexural strength 54 Shear strength 55 Push-out strength 56 Shear bond
strength 56 Overview 57 Microhardness 59 Color and Aesthetics 61
Physicochemical Properties 62 Acknowledgment 66 References 66 4 MTA in
Vital Pulp Therapy 71 Till Dammaschke, Joe H. Camp, and George Bogen
Introduction 72 Advantages 74 Pulp Responses to Capping Materials 74 Direct
Pulp Capping with Calcium Hydroxide 75 Mineral Trioxide Aggregate 77
Physiochemical properties 77 Mode of action in pulp capping and pulpotomy
80 Comparison with calcium hydroxide 83 Pulpotomy in Primary Teeth 85 MTA
Pulpotomy 86 Primary teeth 86 Immature permanent teeth 88 Symptomatic
permanent teeth 90 Pulp Capping in Teeth Diagnosed with Reversible Pulpitis
94 Treatment Considerations 96 Disadvantages 98 Summary 99 Acknowledgment
99 References 100 5 Management of Teeth with Necrotic Pulps and Open Apices
111 Shahrokh Shabahang and David E. Witherspoon Diagnosis in Immature Teeth
111 History of Treating Immature Teeth 114 Infection Control in Immature
Teeth 116 Apexification 118 Calcium Hydroxide Apexification Therapy:
Outcomes 119 Non-Vital Pulp Therapy 121 Root-end closure via the use of
apical barriers 121 Mineral trioxide aggregate apical plug 122 Technical
placement 124 Outcomes 124 References 131 6 Regenerative Endodontics
(Revitalization/Revascularization) 141 Mahmoud Torabinejad, Robert P. Corr,
and George T.-J. Huang Introduction 142 Revascularization after
Replantation and Autotransplantation 143 Revitalization of
Nonvital-Infected Teeth in Animals 145 Clinical Evidence for Revitalization
in Nonvital-Infected Teeth in Humans 152 Potential Role of Stem Cells in
Canal Tissue Generation and Regeneration 160 Role of DPSCs and SCAP in
revitalization and regenerative endodontic treatments 161 Scaffolds and
growth factors for regenerative endodontics (Revitalization) 164 Clinical
Procedures for Pulp Revitalization 168 First appointment 168 Second
appointment 168 Clinical and radiographic follow-up 170 References 170 7
Use of MTA as Root Perforation Repair 177 Mahmoud Torabinejad and Ron Lemon
Introduction 178 Types of Perforation Defects 182 Access
preparation-related perforations 182 Cleaning and shaping related ("strip")
perforations 184 Resorption-related perforations (internal/external) 184
Factors Influencing Prognosis for Repair 187 Size of perforation 187
Location of the perforation 187 Pulp Chamber Perforations 189 Etiologies
189 Prevention 189 Recognition and treatment of pulp chamber perforations
189 Lateral surface repairs 190 Furcation repairs 190 Root Perforations
During Cleaning and Shaping 191 Coronal root perforations 191 Causes,
indicators and prevention 191 Treatment 193 Prognosis 193 Lateral
perforations 194 Causes and indicators 194 Treatment of mid-root
perforation 194 Prognosis 195 Apical perforations 195 Causes and indicators
196 Treatment 197 Prognosis 197 Root Perforation during Post Space
preparation 197 Causes, indicators and prevention 197 Treatment 197
Prognosis 199 Time elapsed since perforation 199 Techniques for Internal
Repair Using MTA 199 Method 199 Summary 202 References 203 8 MTA Root Canal
Obturation 207 George Bogen, Ingrid Lawaty, and Nicholas Chandler
Introduction 208 Charactertics/Properties 210 Mechanisms of action in
obturation 210 Particle size 211 Hydration products and pH 211 Formation of
interstitial layer 212 Fracture resistance 212 Sealing ability and setting
expansion 213 Applications/Uses 214 Conventional obturation 214 Retreatment
216 Obturation prior to surgery 219 Obturation with perforation repair 219
Apexification using MTA obturation 222 Obturation for dental anomalies 225
Obturation Techniques 225 Standard compaction technique 226 Lawaty
technique 229 Auger technique 231 Restorative Considerations 234 Drawbacks
234 Sealers 235 Zinc oxide-eugenol sealers 236 Calcium hydroxide sealers
236 Epoxy resin-based sealers 236 Glass ionomer sealers 237 Silicone-based
sealers 237 Monoblock sealer systems 237 Calcium silicate-based sealers 237
Summary 238 References 239 9 Root-End Fillings Using MTA 251 Seung-Ho Baek
and Su-Jung Shin Introduction of Root-End Filling Materials 252 Purpose of
root-end fillings 252 History of Root-End Filling Materials 253 Amalgam 254
ZOE-based materials: IRM and SuperEBA 254 Resin-based materials: Retroplast
and Geristore 256 Mineral trioxide aggregate (MTA) 256 Gray vs. White MTA
257 New types of MTA-like cements 257 Requirements of Ideal Root-End
Filling Materials 258 Advantages and disadvantages of MTA as a root-end
filling material 258 Advantages of MTA 258 Disadvantages of MTA 259 MTA as
a Root-End Filling Material 260 Cytotoxicity and biocompatibility 260
Bioactivity 263 Sealability 264 Antibacterial effect 265 Clinical
Applications of MTA 265 Retropreparation and root-end filling 265 Cavity
preparation for MTA root-end filling 265 Mixing procedure 266 Methods for
placement of MTA 266 Clinical outcomes 268 Conclusion 272 References 275 10
Calcium Silicate-Based Cements 281 Masoud Parirokh and Mahmoud Torabinejad
Introduction 284 Portland Cement (PC) 285 Chemical composition 285 Physical
properties 286 Antibacterial activity 287 Sealing ability 288
Biocompatibility 288 Cell culture studies 288 Subcutaneous implantation 288
In vivo investigations 289 Clinical applications 289 Limitations 289
Angelus MTA 291 Chemical composition 291 Physical properties 292
Antibacterial activity 293 Sealing ability 293 Biocompatibility properties
293 Cell structure studies 293 Subcutaneous implantation 294 Intraosseous
implantation 294 In vivo investigations 294 Clinical applications 295
Bioaggregate (BA) 295 Chemical composition 295 Physical properties 296
Antibacterial activity 296 Sealing ability 296 Biocompatibility 296 Cell
culture studies 296 Biodentine (BD) 297 Chemical composition 297 Physical
properties 297 Biocompatibility and clinical applications 297 iRoot 298
Chemical composition 298 Physical properties 298 Biocompatibility 299
Calcium Enriched Mixture (CEM) Cement 299 Chemical composition 299 Physical
properties 300 Antibacterial activities 301 Sealing ability 301
Biocompatibility 301 Cell culture studies 301 Skin test and subcutaneous
implantation 302 Intraosseous implantation 302 In vivo investigations 302
Clinical investigations 303 MTA Fillapex 304 Chemical composition 304
Physical properties 304 Antibacterial activities 305 Biocompatibility 306
Cell culture studies 306 Subcutaneous implantation 306 Endo-CPM 306
Chemical composition 307 Physical properties 307 Antibacterial activity 307
Sealing ability 307 Biocompatibility 307 Cell culture studies 307
Subcutaneous implantation 307 In vivo investigations 308 Cimento
Endodontico Rapido (CER) 308 Chemical composition 308 Physical properties
308 Biocompatibility 308 Subcutaneous implantation 308 Endosequence 309
Chemical composition 309 Physical properties 309 Antibacterial activities
310 Sealing ability 310 Biocompatibility 310 Cell culture studies 310
EndoSequence BC Sealer 310 Chemical composition 311 Physical properties 311
Biocompatibility 311 ProRoot Endo Sealer 311 Chemical composition 311
Physical properties 312 MTA Plus 312 Chemical composition 312 Physical
properties 312 Ortho MTA 313 Chemical composition 313 Biocompatibility 313
Cell culture studies 313 MTA Bio 313 Chemical composition 313 Physical
properties 314 Biocompatibility 314 Cell culture studies 314 Subcutaneous
implantation 315 MTA Sealer (MTAS) 315 Chemical compositions and physical
properties 315 Fluoride-Doped MTA Cement 315 Chemical composition 315
Physical properties 316 Sealing ability 316 Capasio 316 Chemical
composition and physical properties 316 Generex A 317 Chemical composition
and physical properties 317 Biocompatibility 317 Cell culture study 317
Ceramicrete-D 317 Chemical composition and physical properties 317
Nano-Modified MTA (NMTA) 318 Chemical composition and physical properties
318 Light-Cured MTA 318 Chemical composition and physical properties 318
Biocompatibility 319 Subcutaneous implantation 319 Calcium Silicate (CS)
319 Chemical composition and physical properties 319 Endocem 320 Chemical
composition and physical properties 320 Biocompatibility 320 Cell culture
study 320 Other Experimental MTA Lookalike Mixtures 320 Conclusion 320
References 321 Index 333