The management of distal tibial fractures is a challenge for surgeons. We report the results of our experience with minimally invasive osteosynthesis of these fractures using the latest generation of Synthes® locking screw plates. This was a prospective study of 13 patients. All were closed fractures associated with a distal fibular fracture. Osteosynthesis was performed on a reduced fracture using traction on an orthopaedic table or an external fixator. All fibular fractures were osteosynthesised. Primary osteosynthesis of these fibular fractures was performed in 61.53% of cases. Osteosynthesis is feasible if reduction criteria are met before synthesis. No complications were observed apart from 2 malunion fractures, with no functional consequences, which occurred at the beginning of our experience. Patients were satisfied in 84.61% of cases and returned to work. Minimally invasive osteosynthesis using a plate with locked screws ensures sufficient and rapid autonomy with fewer complications.