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Periodontitis is a chronic inflammatory disease, characterized by gingival bleeding, periodontal pocket formation connective tissue destruction, and alveolar bone resorption leading to tooth loss. Mitochondria are the intracellular organelles that play a significant role in the cells by metabolizing nutrients and producing the "energy currency" adenosine triphosphate (ATP) and are responsible for various processes.Mitochondrial dysfunction has been defined as the inability of mitochondria to sustain ATP synthesis sufficient to satisfy cellular demands.Periodontopathic bacteria in the…mehr

Produktbeschreibung
Periodontitis is a chronic inflammatory disease, characterized by gingival bleeding, periodontal pocket formation connective tissue destruction, and alveolar bone resorption leading to tooth loss. Mitochondria are the intracellular organelles that play a significant role in the cells by metabolizing nutrients and producing the "energy currency" adenosine triphosphate (ATP) and are responsible for various processes.Mitochondrial dysfunction has been defined as the inability of mitochondria to sustain ATP synthesis sufficient to satisfy cellular demands.Periodontopathic bacteria in the gingivomucosal tissue may functionally activate polymorphonuclear leukocytes (PMNL) that cause increased production of ROS. This has deleterious effects on the mitochondria in the gingivoperiodontal tissues.Recent research also revealed that maintaining mitochondrial dynamics (fission-fusion balance) and mitochondrial function are necessary to treat patients with metabolic syndromes.
Autorenporträt
Le Dr. Aishwarya a obtenu son BDS au Saraswati Dhanwantri Dental College, Parbhani et poursuit actuellement son MDS au Tatyasaheb Kore Dental College, Kolhapur. Elle a présenté des affiches, des articles et des rapports de cas lors de diverses conférences. Elle est très intéressée par le domaine de l'implantologie et souhaite travailler de manière approfondie dans cette branche.