Mitochondrial Outer Membrane Channel and TEM
Soumya Samanta
Broschiertes Buch

Mitochondrial Outer Membrane Channel and TEM

Structural and Functional Analysis by TEM and Electrophysiology

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Mitochondria mediated programmed cell death is still an enigma, largely fuelled by the little known mechanism of important Inter Membrane Space (IMS) protein release in the cytosol from the mitochondria. These proteins start execution phase of apoptosis in many cells, initializing the death of the cell. This book proposes a novel idea and supports it by ample and appropriate evidences.Ceramide (sphingolipid), self assembles to forms a channel in the Mitochondrial Outer Membrane (MOM), to mediate IMS protein release at the onset of apoptosis. This book, for the first time provides direct struct...