A disease of unknown origin - this is the challenge presented by Ménière's disease and taken up by top clinicians and scientists, members and coworkers of The Vestibular Disorder Research Committee organized by The Ministry of Health and Welfare, Japan. They explore the pathophysiology, diagnosis and treatment of Ménière's disease to help physicians faced with treating this intractable ailment. Specialists investigating the etiology of the disease will welcome these reports which clear the picture for future research.
A disease of unknown origin - this is the challenge presented by Ménière's disease and taken up by top clinicians and scientists, members and coworkers of The Vestibular Disorder Research Committee organized by The Ministry of Health and Welfare, Japan. They explore the pathophysiology, diagnosis and treatment of Ménière's disease to help physicians faced with treating this intractable ailment. Specialists investigating the etiology of the disease will welcome these reports which clear the picture for future research.
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Autorenporträt
Ménière's is one of 43 diseases designated by the Japanese Ministry of Health and Welfare as intractable: its causes are unknown and its treatment not yet definitively established. The chairman of the research committee founded by the Ministry has edited reports of the committee's investigations. Their latest findings offer encouragement to practicing physicians confronted with the disease.
Inhaltsangabe
I. Introduction.- 1. Concepts and Diagnostic Criteria of Ménière's Disease.- 2. Ménière's Disease with Bilateral Fluctuating Hearing Loss.- II. Pathophysiology of Ménière's Disease.- 3. The Physical Strength of the Membranous Labyrinth and Its Relation to Endolymphatic Hydrops.- 4. Blood-Flow Regulation in the Vestibulum and Inner Ear Microvasculature in Experimental Hydrops: A Scanning Electron Microscopic Study.- 5. Electrophysiological Aspects of Surgically-Induced Endolymphatic Hydrops.- 6. The Developmental Pattern of Experimental Hydrops in the Endolymphatic Space.- 7. An Animal Model: Ménière's Disease Attack.- 8. An Experimental Study on the Mechanism of the Ménière's Attack: The Influence of High Perilymphatic Potassium Concentration on the Vestibular System.- 9. A Pathohistological Study with Four Kinds of Stress Stimulations on Active Endolymphatic Hydrops in Guinea Pigs.- 10. The Effect of Steroids on Endolymphatic Hydrops Induced by an Immunological Technique.- 11. A Pathoanatomical Study of the Endolymphatic Sac in Ménière's Disease.- 12. Labyrinthine Anomaly and Endolymphatic Hydrops.- 13. An Anatomical Study on Cadavers with a History of Dizziness: Temporal Bone and Some Arteries, Nerve Roots, and Nuclei Related to the Internal Ear.- III. Symptomatology and Diagnosis of Ménière's Disease.- 14. A Statistical Study on Patients with Ménière's Disease Visiting Our Clinic During the Past 10 Years.- 15. Prediction of Prognosis for Hearing in Ménière's Disease.- 16. A Clinical Study of the Diagnosis of the Endolymphatic Hydrops Aspect of Ménière's Disease.- 17. The Significance of the Furosemide VOR Test for Ménière's Disease.- 18. Pathogenesis of the Broad Waveform in Electrocochleograms.- 19. A Test for Predictingthe Next Episode in Ménière's Disease.- 20. The Clinical Epidemiology of Ménière's Disease: Functional Asymmetry.- 21. The Contribution of Otolaryngologists in the Diagnosis of Neuro-Otological Disease: Acoustic Neuromas.- IV. Treatment of Ménière's Disease.- 22. The Treatment of Ménière's Disease with Isosorbide.- 23. Transdermal Scopolamine in the Treatment of Vertiginous Episodes Associated with Ménière's Disease.- 24. The Status of Endolymphatic Sac Surgery.- V. Other Diseases with Endolymphatic Hydrops.- 25. Endolymphatic Hydrops Induced by Chronic Otitis Media.- 26. Sudden Deafness with Bilateral Endolymphatic Hydrops.- 27. Secondary or Idiopathic Endolymphatic Hydrops?.
I. Introduction.- 1. Concepts and Diagnostic Criteria of Ménière's Disease.- 2. Ménière's Disease with Bilateral Fluctuating Hearing Loss.- II. Pathophysiology of Ménière's Disease.- 3. The Physical Strength of the Membranous Labyrinth and Its Relation to Endolymphatic Hydrops.- 4. Blood-Flow Regulation in the Vestibulum and Inner Ear Microvasculature in Experimental Hydrops: A Scanning Electron Microscopic Study.- 5. Electrophysiological Aspects of Surgically-Induced Endolymphatic Hydrops.- 6. The Developmental Pattern of Experimental Hydrops in the Endolymphatic Space.- 7. An Animal Model: Ménière's Disease Attack.- 8. An Experimental Study on the Mechanism of the Ménière's Attack: The Influence of High Perilymphatic Potassium Concentration on the Vestibular System.- 9. A Pathohistological Study with Four Kinds of Stress Stimulations on Active Endolymphatic Hydrops in Guinea Pigs.- 10. The Effect of Steroids on Endolymphatic Hydrops Induced by an Immunological Technique.- 11. A Pathoanatomical Study of the Endolymphatic Sac in Ménière's Disease.- 12. Labyrinthine Anomaly and Endolymphatic Hydrops.- 13. An Anatomical Study on Cadavers with a History of Dizziness: Temporal Bone and Some Arteries, Nerve Roots, and Nuclei Related to the Internal Ear.- III. Symptomatology and Diagnosis of Ménière's Disease.- 14. A Statistical Study on Patients with Ménière's Disease Visiting Our Clinic During the Past 10 Years.- 15. Prediction of Prognosis for Hearing in Ménière's Disease.- 16. A Clinical Study of the Diagnosis of the Endolymphatic Hydrops Aspect of Ménière's Disease.- 17. The Significance of the Furosemide VOR Test for Ménière's Disease.- 18. Pathogenesis of the Broad Waveform in Electrocochleograms.- 19. A Test for Predictingthe Next Episode in Ménière's Disease.- 20. The Clinical Epidemiology of Ménière's Disease: Functional Asymmetry.- 21. The Contribution of Otolaryngologists in the Diagnosis of Neuro-Otological Disease: Acoustic Neuromas.- IV. Treatment of Ménière's Disease.- 22. The Treatment of Ménière's Disease with Isosorbide.- 23. Transdermal Scopolamine in the Treatment of Vertiginous Episodes Associated with Ménière's Disease.- 24. The Status of Endolymphatic Sac Surgery.- V. Other Diseases with Endolymphatic Hydrops.- 25. Endolymphatic Hydrops Induced by Chronic Otitis Media.- 26. Sudden Deafness with Bilateral Endolymphatic Hydrops.- 27. Secondary or Idiopathic Endolymphatic Hydrops?.
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