In the collection of scientific articles the production, processing and sale of products of desert livestock breeding, as well as organizational and economic measures conducted in the sector are investigated. The main types of desert pastures are characterized, their sheep capacity is determined, the norm of allocated pasture lands for one head of Karakul sheep during the year is determined, the reserves for saving sown areas and water resources, increasing the economic efficiency of desert-pasture cattle breeding by introducing innovative technologies for pasture use are justified, the current state of Karakul fur production in Karakalpakstan, the economic efficiency of Karakul and sheep skin processing, as well as of manufacturing of karakul skins in the Republic of Uzbekistan are studied. The quality of karakul skins and the economic efficiency of processing them, as well as the economic efficiency of innovative technology in the processing of karakul skins are studied. The book is intended for researchers, students, farmers, specialists, etc.