Modulation of Oxidative Stress

Biochemical, Physiological and Pharmacological Aspects
Herausgeber: Saso, Luciano; Maccarrone, Mauro; Valacchi, Giuseppe; Giuffre, Alessandro

• Broschiertes Buch

Produktbeschreibung

Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer's disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes chapters on phytotherapy and flavonoids. This book is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 306
• Erscheinungstermin: 7. August 2023
• Englisch
• Abmessung: 276mm x 216mm
• Gewicht: 840g
• ISBN-13: 9780443192470
• ISBN-10: 0443192472
• Artikelnr.: 67404634

Inhaltsangabe

1. Antioxidants as modulators of the Ubiquitin-proteasome system against
aging and proteinopathies
2. Modulation of oxidative stress by S-nitrosation and other thiol
modifications
3. Regulation of Nrf2 Signaling Pathway and the Hallmarks of Aging: An
Overview
4. Fluid redox biomarkers in neurological disease
5. CCM proteins are key players in redox signaling and oxidative stress
regulation in Cerebral
6. Effects of maternal and early life nutrition on redox homeostasis
7. Mitochondria-associated membranes (MAMs) as modulators of oxidative
stress in Alzheimer's disease
8. Oxidative stress biomarkers in human health and disease
9. Modulation of the antioxidant defense system against pathophysiological
redox imbalance in cardiovascular diseases
10. Modulation of cancer cell proliferation by interfering with metabolic
ROS production
11. Modulation of human hydrogen sulfide metabolism by physiological
effectors
12. Intestinal redox and Inflammatory Bowel Disease
13. Applications of Plant-Derived Products in Photodynamic Therapy
14. Hopes and disappointments related to the use of flavonoids in
therapeutical approaches
15. Omega-3 nutritional intervention as therapeutic coadjuvant approach to
improve Rett Syndrome clinical and biochemical features
16. A glance on antioxidants: the role of sulfur amino acids in retinal
disorders
17. Oxidative stress and antioxidant-based therapies in couple infertility
18. Modulation of oxidative stress in psoriasis: Pathophysiology and
therapy