Pfaff

Molecular and Biophysical Mechanisms of Arousal, Alertness and Attention, Volume 1129

Herausgegeben:Pfaff, Donald W; Kieffer, Brigitte

• Broschiertes Buch

Produktbeschreibung

Brain mechanisms for arousal, alertness, and attention underlie all cognitive functions and all emotional expression. This volume discusses the neuroanatomy, neurophysiology, and functional genomics of these states, and the medical consequences of their damage in human patients -- e.g. vegetative states, attention deficit hyperactivity disorder, autism, age-related dementias, mood disorders and sleep disorders. The volume also discusses problems related to vigilance, environmental toxins, fatigue states, circadian rhythms, and sleep/wake physiology, and presents and discusses relevant research techniques, with an emphasis on molecular genetics and on human and animal behavior.

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Produktdetails

• Annals of the New York Academy of Sciences
• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 400
• Erscheinungstermin: 1. Juni 2008
• Englisch
• Abmessung: 253mm x 178mm x 15mm
• Gewicht: 790g
• ISBN-13: 9781573317030
• ISBN-10: 1573317039
• Artikelnr.: 22967822

Autorenporträt

Donald Wells Pfaffis a professor and head of the Laboratory of Neuroscience and Behavior at The Rockefeller University in New York City. Dr. Brigitte Kieffer is a French molecular neurobiologist known for her research of opiate receptors. Her areas of expertise include: molecular psychiatry, addiction, mood disorders, pain, and developmental disorders.

Inhaltsangabe

Preface. Part I: Elementary Central Nervous System Arousal. 1. Concepts and
Mechanisms of Generalized Central Nervous System Arousal. 2. Modulation of
Cortical Activation and Behavioral Arousal by Cholinergic and Orexinergic
Systems. 3. Dopamine Signaling in the Dorsal Striatum is Essential for
Motivated Behaviors. 4. Ablation of the Central Noradrenergic Neurons for
Unraveling Their Roles in Stress and Anxiety. 5. Neural Substrates for
Sexual Preference and Motivation in the Female and Male Rat. 6.
Motivational Influences on the Degree and Direction of Sexual Attraction.
7. Fear Conditioning and LTP in the Amygdala. 8. Insights into the
Pharmacological Potential of Estrogens and Phytoestrogens on Catecholamine
Signaling. 9. Central Thalamic Contributions to Arousal Regulation and
Neurological Disorders of Consciousness. 10. Intrinsic Brain Activity in
Altered States of Consciousness. 11. Detecting Awareness in the Vegetative
State. Part II: The Emotion-Cognition Interface. 12. Neural Mechanisms
Underlying Selective Attention to Threat. 13. Toward a Neurogenetic Theory
of Neuroticism. 14. Gene Expression is Altered in the Lateral Hypothalamus
upon Activation of the Mu Opioid Receptor. 15. Bipolar Disorder as
Maladaptive Arousal. Part III: Alertness and Attention. 16. Measuring
Alertness. 17. Molecular Genetics of Attention. 18. Anatomical Basis for
the Attentional Modulation of Hippocampal Neurons. 19. Cholinergic
Mediation of Attention. 20. Neuronal Mechanisms Underlying Attention
Deficit Hyperactivity Disorder. 21. Placing Neuroanatomical Models of
Executive Function in a Developmental Context. 22. Functional Gene
Variation in the Human Norepinephrine Transporter. Part IV: Circadian
Rhythms in the Activation of Behavior. 23. Circadian and Homeostatic
Factors in Arousal. 24. Hypothalamic Regulation of Sleep and Arousal. 25.
Associations between Sleep Loss and Increased Risk of Obesity and Diabetes.
26. Sleep Deprivation and Vigilant Attention. 27. Sleep and Wakefulness in
Drosophila melanogaster. 28. Why does Consciousness Fade in Early Sleep?
29. Molecular Mechanisms of Sleep and Wakefulness. 30. The In(put)s and
Out(put)s of the Drosophila Circadian Clock. 31. Peripheral Circadian
Oscillators