Molecular and Cell Biology - Obule, Isioh
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Globally, breast cancer is ubiquitous and regarded as a leading cause of death amongst other causes of death. It plays a role in several aberrant genes seen in the tumorigenesis pathway, thus making it heterogenic. An example of this gene is the HDAC1 gene, which is a multifunctional protein and plays a role in gene expression regulation. Using the CRISPR/Cas9 system, a remarkable gene editing approach essential in identifying and validating genomic targets with the potential to be tumoricidal, the role of HDAC1 was investigated in a breast cancer cell line, MCF-7.

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Produktbeschreibung
Globally, breast cancer is ubiquitous and regarded as a leading cause of death amongst other causes of death. It plays a role in several aberrant genes seen in the tumorigenesis pathway, thus making it heterogenic. An example of this gene is the HDAC1 gene, which is a multifunctional protein and plays a role in gene expression regulation. Using the CRISPR/Cas9 system, a remarkable gene editing approach essential in identifying and validating genomic targets with the potential to be tumoricidal, the role of HDAC1 was investigated in a breast cancer cell line, MCF-7.
Autorenporträt
My name is Isioh Miley Obule. I had my Bachelors Degree in Pharmacology and Therapeutics in Nigeria. In 2022, I proceeded to do a Masters in Pharmacology in the United Kingdom, where I graduated with a distinction.