Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. It will enable them to understand how basic physical concepts can be used in the investigation of biological problems. All students who have taken physical chemistry and calculus courses will find this book accessible. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples including protein folding, enzyme catalysis and ion channel permeation.
Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. It will enable them to understand how basic physical concepts can be used in the investigation of biological problems. All students who have taken physical chemistry and calculus courses will find this book accessible. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples including protein folding, enzyme catalysis and ion channel permeation.
MEYER B. JACKSON is Professor of Physiology at the University of Wisconsin Medical School. He has been teaching graduate level biophysics for nearly 25 years.
Inhaltsangabe
Preface; Acknowledgements; 1. Global transitions in proteins; 2. Molecular forces in biological structures; 3. Conformations of macromolecules; 4. Molecular associations; 5. Allosteric interactions; 6. Diffusion and Brownian motion; 7. Fundamental rate processes; 8. Association kinetics; 9. Multi-state kinetics; 10. Enzyme catalysis; 11. Ions and counter-ions; 12. Fluctuations; 13. Ion permeation and membrane potential; 14. Ion permeation and channel structure; 15. Cable theory; 16. Action potentials; References; Appendix 1. Expansions and series; Appendix 2. Matrix algebra; Appendix 3. Fourier analysis; Appendix 4. Gaussian integrals; Appendix 5. Hyperbolic functions; Appendix 6. Polar and spherical coordinates.
Preface; Acknowledgements; 1. Global transitions in proteins; 2. Molecular forces in biological structures; 3. Conformations of macromolecules; 4. Molecular associations; 5. Allosteric interactions; 6. Diffusion and Brownian motion; 7. Fundamental rate processes; 8. Association kinetics; 9. Multi-state kinetics; 10. Enzyme catalysis; 11. Ions and counter-ions; 12. Fluctuations; 13. Ion permeation and membrane potential; 14. Ion permeation and channel structure; 15. Cable theory; 16. Action potentials; References; Appendix 1. Expansions and series; Appendix 2. Matrix algebra; Appendix 3. Fourier analysis; Appendix 4. Gaussian integrals; Appendix 5. Hyperbolic functions; Appendix 6. Polar and spherical coordinates.
Rezensionen
'... would be a valuable addition to the library of any research lab at the physical end of biochemistry. ... The language used in the book is extremely clear, and a mathematical approach is combined with clear links to real biochemistry ...' Chemistry world
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