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Ever since the Great Irish Potato Famine in 1845, late blight disease of potato, caused by the oomycete Phytophthora infestans, has remained one of the most serious threats to food security in many countries around the world and research is ongoing to find novel ways of fighting this challenging disease. This work contributes to the better understanding of the interplay between the plant and the pathogen at the molecular level to bring fresh insights into the functioning of this important pathosystem.