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A wonderful walk into the world of eye genetics. A 'role model' for all researchers. This piece demonstrates that other known and unknown genes may contribute to Primary Congenital Glaucoma (PCG) pathogenesis. Lack of CYP1B1 gene mutations in some patients stresses the need to identify other responsible candidates. More analysis and screening may be needed and to study Pigmentary Dispersion Syndrome (PDS) genetics.