Molecular Biology of Diabetes, Part II
Insulin Action, Effects on Gene Expression and Regulation, and Glucose Transport
Herausgegeben:Draznin, Boris; LeRoith, Derek
Molecular Biology of Diabetes, Part II
Insulin Action, Effects on Gene Expression and Regulation, and Glucose Transport
Herausgegeben:Draznin, Boris; LeRoith, Derek
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These comprehensive yet concise collections of articles by world experts survey the latest findings on the molecular biology of diabetes and insulin action and synthesize a coherent understanding of the subject. Topics include the etiology of type I and type II diabetes, molecular and cellular aspects of insulin action, and the mechanism of the insulin-stimulated glucose uptake.
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These comprehensive yet concise collections of articles by world experts survey the latest findings on the molecular biology of diabetes and insulin action and synthesize a coherent understanding of the subject. Topics include the etiology of type I and type II diabetes, molecular and cellular aspects of insulin action, and the mechanism of the insulin-stimulated glucose uptake.
Produktdetails
- Produktdetails
- Verlag: Humana / Humana Press / Springer, Berlin
- Artikelnr. des Verlages: 978-1-61737-004-5
- 1995
- Seitenzahl: 576
- Erscheinungstermin: 12. Dezember 2011
- Englisch
- Abmessung: 229mm x 152mm x 31mm
- Gewicht: 863g
- ISBN-13: 9781617370045
- ISBN-10: 1617370045
- Artikelnr.: 32201043
- Verlag: Humana / Humana Press / Springer, Berlin
- Artikelnr. des Verlages: 978-1-61737-004-5
- 1995
- Seitenzahl: 576
- Erscheinungstermin: 12. Dezember 2011
- Englisch
- Abmessung: 229mm x 152mm x 31mm
- Gewicht: 863g
- ISBN-13: 9781617370045
- ISBN-10: 1617370045
- Artikelnr.: 32201043
Section I: Molecular and Cellular Aspects of Insulin Action. Mutations in
the Insulin Receptor Gene in Patients with Genetic Syndromes of Extreme
Insulin Resistance. The Insulin Receptor: Structure/Function Relationship.
Identification of Diabetes-Related Genes by Subtraction Cloning. The
Insulin Receptor-Related. Structure of Insulin Receptor Substrate 1 and
Role in Insulin Signaling as a Docking Protein for SH2 Domain-Containing
Proteins. Phosphatidylinositol 3'-Kinase and Insulin Action. The Role of
p21ras in Insulin Signaling. MAP Kinase Pathways and Insulin Action. Raf-1
Kinase. Role of Phosphoprotein Phosphatase 1 (PP-1) in the Mechanism of
Insulin Action. The Role (or Lack Thereof) of Protein Kinase C in Insulin
Action. Regulation of the Phosphoenolpyruvate Carboxykinase Gene by
Insulin. Regulation of Gene 33 Expression by Insulin. Distinct Elements in
the PEPCK and Amylase Genes Mediate the Diabetes and Carbohydrate Response:
Potential Role of IRE-ABP in Mediating the Dietary Response. Molecular
Aspects of Insulin-Regulated Hepatic Growth. Endocytosis and Cellular
Processing of Insulin-Receptor Complexes: Mechanisms and Biological
Functions. Chiroinositol Deficiency and Insulin Resistance: A Clinical
Perspective. Regulation of c-fos Gene Expression by Insulin in Neurons.
Molecular Comparison of the Insulin and IGF-I Receptors. Insulin-Like
Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in
Diabetes. Structure-Function Properties of Insulin/IGF-I Hybrid Receptors.
Section II: Molecular Mechanisms of the Insulin-Regulatable Glucose
Transport. GLUT-4 Glucose Transporters and Insulin Action in Humans:
Regulation at the Level of Gene Expression and Cellular Trafficking. Mutant
GLUT-4 and the Role of GLUT-4 Phosphorylation in Controlling Glucose
Transport. GLUT-4 Phosphorylation: Effects of Phosphorylation on Glucose
Transport and Intrinsic Activity. Glucose Transporters of Muscle Cells in
Culture: Developmental Regulation and Modulation by Lipoic Acid, an
Anti-Hyperglycemic Agent. Expression of the GLUT-4 Glucose Transporter in
Diabetes. Index.
the Insulin Receptor Gene in Patients with Genetic Syndromes of Extreme
Insulin Resistance. The Insulin Receptor: Structure/Function Relationship.
Identification of Diabetes-Related Genes by Subtraction Cloning. The
Insulin Receptor-Related. Structure of Insulin Receptor Substrate 1 and
Role in Insulin Signaling as a Docking Protein for SH2 Domain-Containing
Proteins. Phosphatidylinositol 3'-Kinase and Insulin Action. The Role of
p21ras in Insulin Signaling. MAP Kinase Pathways and Insulin Action. Raf-1
Kinase. Role of Phosphoprotein Phosphatase 1 (PP-1) in the Mechanism of
Insulin Action. The Role (or Lack Thereof) of Protein Kinase C in Insulin
Action. Regulation of the Phosphoenolpyruvate Carboxykinase Gene by
Insulin. Regulation of Gene 33 Expression by Insulin. Distinct Elements in
the PEPCK and Amylase Genes Mediate the Diabetes and Carbohydrate Response:
Potential Role of IRE-ABP in Mediating the Dietary Response. Molecular
Aspects of Insulin-Regulated Hepatic Growth. Endocytosis and Cellular
Processing of Insulin-Receptor Complexes: Mechanisms and Biological
Functions. Chiroinositol Deficiency and Insulin Resistance: A Clinical
Perspective. Regulation of c-fos Gene Expression by Insulin in Neurons.
Molecular Comparison of the Insulin and IGF-I Receptors. Insulin-Like
Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in
Diabetes. Structure-Function Properties of Insulin/IGF-I Hybrid Receptors.
Section II: Molecular Mechanisms of the Insulin-Regulatable Glucose
Transport. GLUT-4 Glucose Transporters and Insulin Action in Humans:
Regulation at the Level of Gene Expression and Cellular Trafficking. Mutant
GLUT-4 and the Role of GLUT-4 Phosphorylation in Controlling Glucose
Transport. GLUT-4 Phosphorylation: Effects of Phosphorylation on Glucose
Transport and Intrinsic Activity. Glucose Transporters of Muscle Cells in
Culture: Developmental Regulation and Modulation by Lipoic Acid, an
Anti-Hyperglycemic Agent. Expression of the GLUT-4 Glucose Transporter in
Diabetes. Index.
Section I: Molecular and Cellular Aspects of Insulin Action. Mutations in
the Insulin Receptor Gene in Patients with Genetic Syndromes of Extreme
Insulin Resistance. The Insulin Receptor: Structure/Function Relationship.
Identification of Diabetes-Related Genes by Subtraction Cloning. The
Insulin Receptor-Related. Structure of Insulin Receptor Substrate 1 and
Role in Insulin Signaling as a Docking Protein for SH2 Domain-Containing
Proteins. Phosphatidylinositol 3'-Kinase and Insulin Action. The Role of
p21ras in Insulin Signaling. MAP Kinase Pathways and Insulin Action. Raf-1
Kinase. Role of Phosphoprotein Phosphatase 1 (PP-1) in the Mechanism of
Insulin Action. The Role (or Lack Thereof) of Protein Kinase C in Insulin
Action. Regulation of the Phosphoenolpyruvate Carboxykinase Gene by
Insulin. Regulation of Gene 33 Expression by Insulin. Distinct Elements in
the PEPCK and Amylase Genes Mediate the Diabetes and Carbohydrate Response:
Potential Role of IRE-ABP in Mediating the Dietary Response. Molecular
Aspects of Insulin-Regulated Hepatic Growth. Endocytosis and Cellular
Processing of Insulin-Receptor Complexes: Mechanisms and Biological
Functions. Chiroinositol Deficiency and Insulin Resistance: A Clinical
Perspective. Regulation of c-fos Gene Expression by Insulin in Neurons.
Molecular Comparison of the Insulin and IGF-I Receptors. Insulin-Like
Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in
Diabetes. Structure-Function Properties of Insulin/IGF-I Hybrid Receptors.
Section II: Molecular Mechanisms of the Insulin-Regulatable Glucose
Transport. GLUT-4 Glucose Transporters and Insulin Action in Humans:
Regulation at the Level of Gene Expression and Cellular Trafficking. Mutant
GLUT-4 and the Role of GLUT-4 Phosphorylation in Controlling Glucose
Transport. GLUT-4 Phosphorylation: Effects of Phosphorylation on Glucose
Transport and Intrinsic Activity. Glucose Transporters of Muscle Cells in
Culture: Developmental Regulation and Modulation by Lipoic Acid, an
Anti-Hyperglycemic Agent. Expression of the GLUT-4 Glucose Transporter in
Diabetes. Index.
the Insulin Receptor Gene in Patients with Genetic Syndromes of Extreme
Insulin Resistance. The Insulin Receptor: Structure/Function Relationship.
Identification of Diabetes-Related Genes by Subtraction Cloning. The
Insulin Receptor-Related. Structure of Insulin Receptor Substrate 1 and
Role in Insulin Signaling as a Docking Protein for SH2 Domain-Containing
Proteins. Phosphatidylinositol 3'-Kinase and Insulin Action. The Role of
p21ras in Insulin Signaling. MAP Kinase Pathways and Insulin Action. Raf-1
Kinase. Role of Phosphoprotein Phosphatase 1 (PP-1) in the Mechanism of
Insulin Action. The Role (or Lack Thereof) of Protein Kinase C in Insulin
Action. Regulation of the Phosphoenolpyruvate Carboxykinase Gene by
Insulin. Regulation of Gene 33 Expression by Insulin. Distinct Elements in
the PEPCK and Amylase Genes Mediate the Diabetes and Carbohydrate Response:
Potential Role of IRE-ABP in Mediating the Dietary Response. Molecular
Aspects of Insulin-Regulated Hepatic Growth. Endocytosis and Cellular
Processing of Insulin-Receptor Complexes: Mechanisms and Biological
Functions. Chiroinositol Deficiency and Insulin Resistance: A Clinical
Perspective. Regulation of c-fos Gene Expression by Insulin in Neurons.
Molecular Comparison of the Insulin and IGF-I Receptors. Insulin-Like
Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in
Diabetes. Structure-Function Properties of Insulin/IGF-I Hybrid Receptors.
Section II: Molecular Mechanisms of the Insulin-Regulatable Glucose
Transport. GLUT-4 Glucose Transporters and Insulin Action in Humans:
Regulation at the Level of Gene Expression and Cellular Trafficking. Mutant
GLUT-4 and the Role of GLUT-4 Phosphorylation in Controlling Glucose
Transport. GLUT-4 Phosphorylation: Effects of Phosphorylation on Glucose
Transport and Intrinsic Activity. Glucose Transporters of Muscle Cells in
Culture: Developmental Regulation and Modulation by Lipoic Acid, an
Anti-Hyperglycemic Agent. Expression of the GLUT-4 Glucose Transporter in
Diabetes. Index.