Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson's, Alzheimer's and Huntington's disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases.
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson's, Alzheimer's and Huntington's disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases.
This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases.
Produktdetails
Produktdetails
Progress in Molecular Biology and Translational Science Volume 107
David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid ß-protein (Alzheimer's disease) and a-synuclein (Parkinson's disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Co-Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.
Inhaltsangabe
Neuropathology and imaging Harry Vinters
Neuropathology and imaging Thompson, Paul
Age-dependence of neurodegenerative diseases (organismal genetics) Tanzi, Rudolph
AD Dominic Walsh
PD Guo, Ming
PD Rochet, Chris and
Prion I: Human Surewicz, Witold
Prion II: Yeast Tuite, Mick
Cerebral amyloid angiopathy Cerebral amyloid angiopathy Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee
Age-dependence of neurodegenerative diseases (organismal genetics) Tanzi, Rudolph
AD Dominic Walsh
PD Guo, Ming
PD Rochet, Chris and
Prion I: Human Surewicz, Witold
Prion II: Yeast Tuite, Mick
Cerebral amyloid angiopathy Cerebral amyloid angiopathy Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee
Membrane Pores Kagan, Bruce
Unfolded protein response
ALS Dokholyan, Nikolay
CAG-repeat diseases Chris Ross
Mitochondria Lee Martin
Rezensionen
Praise for the series: "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
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