Sumaya Abed Ali, Rana Al- Shamari

Molecular Characterization of Antibiotic Resistance P. aeruginosa

Isolated from Al-Sader Medical City at Al- Najaf Province

• Broschiertes Buch

Produktbeschreibung

Pseudomonas aeruginosa is a leading cause of nosocomial infections; it is highly resistant to many antibiotics by several different mechanisms. The main purpose of this study was to determine the dissemination of (MDR) Sader Medical City in Al- Najaf province .A total of 200 clinical and hospital environment samples, 32 isolates were identified as P. aeruginosa by the Oxidase test and confirmed by VITEK-2 compact system. Susceptibility testing was done using the VITEK-2 compact system. The isolates were examined for the presence of extended spectrum beta-lactamases (ESBLs), (OXA, CTX- M, TEM, SHV ), carbapenemases class B (IMP, VIM), and class A (KPC), in addition, aminoglycosides resistant genes(aac(3')-I aac(6')-Ib, aac(6')-I) by PCR. 8 isolates exhibited PDR, 2 isolates exhibited XDR and 3 displayed MDR. The majority (20/32) of the P. aeruginosa were positive for blaOXA. In addition, 10 isolates harbored blaCTX-M and 7 isolates were positive for the carbapenemase gene blavim.The blaIMP and blaKPC were not detected. All bacteria harboring blaVIM gene has a PDR resistant phenotype. Fifteen isolates contained at least 1 aminoglycosides resistance gene.

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Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 112
• Erscheinungstermin: 7. Mai 2024
• Englisch
• Abmessung: 220mm x 150mm x 7mm
• Gewicht: 185g
• ISBN-13: 9786207488292
• ISBN-10: 6207488296
• Artikelnr.: 70839642

Autorenporträt

I am a microbiologist, with a master degree in Department of Microbiology, College of Medicine, University of Kufa.