59,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 1-2 Wochen
payback
30 °P sammeln
  • Broschiertes Buch

Human platelet HPA-1 polymorphism is embedded in the N-terminal plexin/semaphorin/integrin (PSI) domain of the beta3 chain of the platelet integrin IIbbeta3. HPA-1 polymorphism is responsible for neonatal alloimmune thrombocytopenia (NAITP). T-helper response drives anti-HPA-1a production and the putative dominant T-helper epitope is likely to be an important contributory factor in the immunogenicity of HPA-1a. This book provides detailed insight into the molecular mechanism behind of anti-HPA-1a platelet alloimmunization.

Produktbeschreibung
Human platelet HPA-1 polymorphism is embedded in the N-terminal plexin/semaphorin/integrin (PSI) domain of the beta3 chain of the platelet integrin IIbbeta3. HPA-1 polymorphism is responsible for neonatal alloimmune thrombocytopenia (NAITP). T-helper response drives anti-HPA-1a production and the putative dominant T-helper epitope is likely to be an important contributory factor in the immunogenicity of HPA-1a. This book provides detailed insight into the molecular mechanism behind of anti-HPA-1a platelet alloimmunization.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Autorenporträt
Gholamreza Anani Sarab (PhD, MSc, PG Diploma). Assistant Professor in Birjand University of Medical Sciences. PhD in Immunohaematology, University of Aberdeen-UK. Postgraduate Diploma in Medical Molecular Genetics, University of Aberdeen-UK. MSc in Medical Immunology, Tehran University of Medical Sciences, Tehran-Iran.