Steve J Winder

Molecular Mechanisms of Muscular Dystrophies

• Broschiertes Buch

Produktbeschreibung

This book presents a collection of chapters covering a spectrum of muscular dystrophies and one myopathy that represent most of the major muscular dystrophies, and, in particular, those where a molecular understanding of the underlying mechanisms is most advanced.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 250
• Erscheinungstermin: 2. Dezember 2019
• Englisch
• Abmessung: 229mm x 152mm x 13mm
• Gewicht: 340g
• ISBN-13: 9780367446376
• ISBN-10: 0367446375
• Artikelnr.: 58442564

Autorenporträt

Steve J. Winder

Inhaltsangabe

1. Structure and Function of the Dystrophin-Glycoprotein Complex 2. The
Structure and Function of Dystrophin 3. Utrophin in the Therapy of Duchenne
Muscular Dystrophy 4. Syntrophin: A Molecular Adaptor Conferring a
Signaling Role to the Dystrophin-Associated Protein Complex 5. Molecular
and Functional Diversity of Dystrobrevin-Containing Complexes 6.
Commonalities and Differences in Muscular Dystrophies: Mechanisms and
Molecules Involved in Merosin-Deficient Congenital Muscular Dystrophy 7.
Glycosylation and Muscular Dystrophy 8. Overview of the Limb-Girdle
Muscular Dystrophies and Dysferlinopathy 9. Caveolin-3 and Limb-Girdle
Muscular Dystrophy 10. The Sarcoglycans 11. Sarcomeric Proteins in LGMD 12.
Lamins and Emerin in Muscular Dystrophy: The Nuclear Envelope Connection
13. Distinct Mechanisms Downstream of the Repeat Expansion Are Implicated
in the Molecular Basis of Myotonic Dystrophy Type 1 14. Spinal Muscular
Atrophy 15. The Pathophysiological Role of Impaired Calcium Handling in
Muscular Dystrophy 16. Cell Adhesion and Signalling in the Muscular
Dystrophies 17. Gene Therapies for Muscular Dystrophies 18. Cell Therapies
for Muscular Dystrophy