Molecular Modeling at the Atomic Scale

Methods and Applications in Quantitative Biology
Herausgeber: Zhou, Ruhong

• Gebundenes Buch

Produktbeschreibung

This timely summary reflects the recent advances in bridging novel algorithms and high performance computing with characterization of important biological processes, such as folding dynamics of key proteins.

---

Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 388
• Erscheinungstermin: 21. August 2014
• Englisch
• Abmessung: 234mm x 152mm x 25mm
• Gewicht: 703g
• ISBN-13: 9781466562950
• ISBN-10: 1466562951
• Artikelnr.: 39612698

Autorenporträt

Ruhong Zhou

Inhaltsangabe

Introduction. I. Advanced Simulation Techniques. Novel sampling algorithms
for molecular dynamics. Advanced free energy perturbation techniques.
Massively parallel supercomputers and software for molecular dynamics.
Development of modern polarizable force fields. MM-QM methods for enzymatic
reactions. II. Self-Assembly of Biomolecules. Protein folding dynamics and
pathways. Folding kinetics with Markov State Models. RNA folding.
Misfolding and aggregation. III. Biomolecular Interactions. Protein-protein
interactions. Protein-nanoparticle interactions. Ligand-receptor binding.
RNA(DNA)-protein interactions. IV. Other Applications in Molecular Biology.
Modeling of DNA sequencing with nanopore. Biological (confined) water
dynamics. Enzymatic reaction pathways.