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Design, Syntheses and Molecular Modeling studies on Anti-HIV and Anti-HBV nucleosides with special focus on understanding the underlying mechanism of their action as well as inaction. A better understanding of their mechanism will help facilitate the better designing of novel drugs to combat against them. Molecular modeling as well as Molecular Dynamics studies were conducted to ascertain their mode of binding and calculate their binding affinities and to find a correlation between their binding affinities and their biological activity.

Produktbeschreibung
Design, Syntheses and Molecular Modeling studies on Anti-HIV and Anti-HBV nucleosides with special focus on understanding the underlying mechanism of their action as well as inaction. A better understanding of their mechanism will help facilitate the better designing of novel drugs to combat against them. Molecular modeling as well as Molecular Dynamics studies were conducted to ascertain their mode of binding and calculate their binding affinities and to find a correlation between their binding affinities and their biological activity.
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Autorenporträt
Dr. Vikas Yadav was born in INDIA. He received his B.Pharm. Sc. from University of Mumbai in 2000 and then proceeded for his Ph.D in Pharmaceutical and Biomedical Sciences,at University of Georgia, Athens, USA (2006). His present interests are in coding and prototype development.