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The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a vast amount of information on motor mechanisms and potential biomedical and nanobiotechnological applications, this handbook fulfills the need for a collection of current research results on the functionality, regulation, and interactions of cytoskeletal, DNA, and…mehr

Produktbeschreibung
The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a vast amount of information on motor mechanisms and potential biomedical and nanobiotechnological applications, this handbook fulfills the need for a collection of current research results on the functionality, regulation, and interactions of cytoskeletal, DNA, and rotary motors. Here, leading experts present a concise insight, ranging from atomic structure, biochemistry, and biophysics to cell biology, developmental biology and pathology. Basic principles and applications make this book a valuable reference tool for researchers, professionals, and clinicians alike - all set to become a "classic" in the years to come.
Jüngste Erkenntnisse über Molekulare Motoren vertiefen das Verständnis für zahlreiche biologische und medizinische Phänomene: die Mobilität von Zellen, Organell-Bewegungen, Virustransport, Asymmetrie, Myopathien und Sinnesstörungen gehen gleichermaßen auf die Funktion oder Fehlfunktion einer faszinierenden Miniatur-Mechanik zurück. Der Bedarf nach einem Handbuch über Zytoskelett-, DNA- und Rotations-Motoren, das sowohl Grundlagen als auch Anwendungen zusammenfaßt, hat sich in den letzten Jahren vervielfacht - hier ist es! Ob Funktion, Regulation oder Wechselwirkungen: der international bekannte Herausgeber sowie sein erstklassiges Autorenteam spannen den thematischen Bogen von atomaren Strukturen, Biochemie und Biophysik über Zellbiologie hin zu Entwicklungsbiologie, Pathologie und Bionanotechnologie - beste Voraussetzungen für einen echten "Klassiker"!
Rezensionen
"...essential reading for graduate students in the field of cell motility and molecular motors...recommend it enthusiastically..." - Nature Cell Biology, Vol. 6, 2004

"Molecular Motors is an excellent source book that provides much-needed up-to-date introduction and an important snapshot of current knowledge of a rapidly expanding field of biology." - Edgar Meyhofer, Department of mechanical Engineering, University of Michigan, Advanced Materials, September3, 2004

"...a unique collection of chapters written by leaders who are well versed with the field...Overall, the book will be an excellent source for both professional and general readers, providing a wide range of in-depth insights into the structure, mechanism, function, and role of molecular motors in the life cycle of a cell." - Quarterly Review of Biology, March-May 2005