With applications ranging from drug discovery and medical diagnostics to gas sensing and chemical/biological/environmental risk monitoring, molecular sensors or chemosensors offer a valuable tool for engineers and scientists, enabling new MEMS/NEMS devices and providing a variety of nanoscale sensing techniques. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the…mehr
With applications ranging from drug discovery and medical diagnostics to gas sensing and chemical/biological/environmental risk monitoring, molecular sensors or chemosensors offer a valuable tool for engineers and scientists, enabling new MEMS/NEMS devices and providing a variety of nanoscale sensing techniques. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of molecular sensors in nano/micro fabrication techniques, including MEMS, BioMEMS, MicroTAS, etc. The miniaturization of versatile molecular sensors opens up a new range of nanoscale sensing technology, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover data analysis techniques and the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical device engineering. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike.
Xiaojing(John) Zhang is an Associate Professor in the Department of Biomedical Engineering at the University of Texas of Austin (UT Austin). He received his Ph.D. from Stanford University, California, and was a Research Scientist at Massachusetts Institute of Technology (MIT) before joining the faculty at UT Austin. Dr. Zhang's research focuses on integrating Micro-electro-mechanical Systems (MEMS), nano-materials, micro-imaging and biosensors to provide innovative solutions to critical healthcare issues. Dr. Zhang has actively engaged in teaching new concepts and methods in these emerging biomedical engineering frontiers and has demonstrated innovation and excellence in engineering education. The materials presented in this textbook are based on his lecture notes while teaching a popular course on molecular sensors and nanodevices at UT Austin for the past 8 years. He has a track record for developing both core and emerging engineering curriculum along with developing well-funded research programs with fellow students. Among his numerous awards, Dr. Zhang received the Wallace H. Coulter Foundation Early Career Award in Biomedical Engineering, NSF CAREER award, DARPA Young Faculty Award among many others. To recognize his accomplishment in research and education, Dr. Zhang was selected to attend the prestigious US National Academy of Engineering, Frontiers of Engineering (NAE FOE) program in 2011, the NAE Frontiers of Engineering Education (NAE FOEE) program in 2012, and subsequently China-America Frontiers of Engineering Symposium (CAFOE) program in 2013. As an active member in his professional community, Dr. Zhang has served on numerous international conference organizing committees and editorial boards. He is an editor for ASME/IEEE Journal of Microelectromechanical Systems (JMEMS) and an associate editor Biomedical Microdevices.
Inhaltsangabe
1. Introduction to Molecular Sensors Introduction2. Fundamentals of Nano/Microfabrication and Scale Effect 3. Microfluidics basics and total analytical systems4. Electrical transducers: electrochemical sensors and FET-based molecular sensors5. Optical transducers: optical molecular sensors and optical spectroscopy6. Mechanical transducers: cantilevers, acoustic wave sensors and thermal sensors 7. Implantable sensors
