The large volume requirements for high quality ABO and Rh(D) typing reagents can now be supplied by selected monoclonal antibodies using hybridoma technology. In this book two efficient methods for the industrial production of Monoclonal antibody is described. This products have major advantages in lot-to-lot consistency in both potency and specificity, and have minimal processing requirements no defibrination, delipidisation or absorption of unwanted anibodies.