This Book provides a detailed description of Application Software which predicts Mosquito-Borne Disease incidence such as Malaria, Dengue, Filariasis, Encephalitis, etc., in any particular area, based on the climatic conditions like Rainfall, Humidity, Temperature, etc., of that area. Though many diseases are influenced by the environmental conditions, Mosquito borne diseases are more sensitive, as environmental conditions affect the infecting pathogens,human hosts and the insects and other intermediate hosts that transmit these diseases.The spread of Mosquito borne diseases are influenced by the change in climate, directly and indirectly. Hence, in this study we made an attempt to establish the association between meteorological variables and disease incidence.