Mosquito Gene Drives and the Malaria Eradication Agenda
Herausgeber: Carballar-Lejarazú, Rebeca
Mosquito Gene Drives and the Malaria Eradication Agenda
Herausgeber: Carballar-Lejarazú, Rebeca
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This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission.
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This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission.
Produktdetails
- Produktdetails
- Verlag: Jenny Stanford Publishing
- Seitenzahl: 360
- Erscheinungstermin: 24. Februar 2023
- Englisch
- Abmessung: 229mm x 152mm x 22mm
- Gewicht: 667g
- ISBN-13: 9789814968331
- ISBN-10: 9814968331
- Artikelnr.: 67260267
- Verlag: Jenny Stanford Publishing
- Seitenzahl: 360
- Erscheinungstermin: 24. Februar 2023
- Englisch
- Abmessung: 229mm x 152mm x 22mm
- Gewicht: 667g
- ISBN-13: 9789814968331
- ISBN-10: 9814968331
- Artikelnr.: 67260267
Dr. Rebeca Carballar-Lejarazú's research is focused on insect molecular genetics, vector biology, and the development of synthetic approaches to prevent transmission of mosquito-borne diseases. She has used several genetic strategies such as transposon-based random integration, phiC31 docking-site integration and CRISPR/Cas9 site-specific genome editing technologies to develop transgenic mosquitoes. Dr. Carballar-Lejarazú is currently working on the development, optimization, and evaluation of a CRISPR/Cas9 gene drive system to engineer mosquitoes that resist malaria parasites (population modification/replacement) in two main malaria African vectors Anopheles gambiae and Anopheles coluzzii. Her insect interests have been centered mainly on vector mosquitoes. However, in 2014, she started a collaboration with Professor Sonqing Wu to study biopesticides to control crop pests in China.
SECTION I THE MALARIA CHALLENGE 1. Current Scenario of Malaria and the
Transformative Power of Gene Drive-Based Technologies SECTION II MOSQUITO
GENETIC MANIPULATION FOR MALARIA 2. Transgenesis and Paratransgenesis for
the Control of Malaria 3. Gene Drives for Anopheles Mosquitoes 4. Gene
Drive Applications for Malaria Control SECTION III GENE DRIVE MOSQUITO
TRIALS 5. Large Cage Trials of Gene Drive Mosquitoes: Does Size Matter? 6.
Field Trial Site Selection for Mosquitoes with Gene Drive: Geographic,
Ecological, and Population Genetic Considerations 7. Modeling Priorities as
Gene Drive Mosquito Projects Transition from Lab to Field SECTION IV RISK
ASSESSMENT AND COMMUNITY ENGAGEMENT 8. Probabilistic Ecological Risk
Assessment: An Overview of the Process 9. Community Engagement and Mosquito
Gene Drives SECTION V POLICY, REGULATORY, AND ETHICAL CONSIDERATIONS 10.
Review of International Regulatory Instruments and Processes 11. Gene Drive
Mosquitoes: Ethical and Political Considerations
Transformative Power of Gene Drive-Based Technologies SECTION II MOSQUITO
GENETIC MANIPULATION FOR MALARIA 2. Transgenesis and Paratransgenesis for
the Control of Malaria 3. Gene Drives for Anopheles Mosquitoes 4. Gene
Drive Applications for Malaria Control SECTION III GENE DRIVE MOSQUITO
TRIALS 5. Large Cage Trials of Gene Drive Mosquitoes: Does Size Matter? 6.
Field Trial Site Selection for Mosquitoes with Gene Drive: Geographic,
Ecological, and Population Genetic Considerations 7. Modeling Priorities as
Gene Drive Mosquito Projects Transition from Lab to Field SECTION IV RISK
ASSESSMENT AND COMMUNITY ENGAGEMENT 8. Probabilistic Ecological Risk
Assessment: An Overview of the Process 9. Community Engagement and Mosquito
Gene Drives SECTION V POLICY, REGULATORY, AND ETHICAL CONSIDERATIONS 10.
Review of International Regulatory Instruments and Processes 11. Gene Drive
Mosquitoes: Ethical and Political Considerations
SECTION I THE MALARIA CHALLENGE 1. Current Scenario of Malaria and the
Transformative Power of Gene Drive-Based Technologies SECTION II MOSQUITO
GENETIC MANIPULATION FOR MALARIA 2. Transgenesis and Paratransgenesis for
the Control of Malaria 3. Gene Drives for Anopheles Mosquitoes 4. Gene
Drive Applications for Malaria Control SECTION III GENE DRIVE MOSQUITO
TRIALS 5. Large Cage Trials of Gene Drive Mosquitoes: Does Size Matter? 6.
Field Trial Site Selection for Mosquitoes with Gene Drive: Geographic,
Ecological, and Population Genetic Considerations 7. Modeling Priorities as
Gene Drive Mosquito Projects Transition from Lab to Field SECTION IV RISK
ASSESSMENT AND COMMUNITY ENGAGEMENT 8. Probabilistic Ecological Risk
Assessment: An Overview of the Process 9. Community Engagement and Mosquito
Gene Drives SECTION V POLICY, REGULATORY, AND ETHICAL CONSIDERATIONS 10.
Review of International Regulatory Instruments and Processes 11. Gene Drive
Mosquitoes: Ethical and Political Considerations
Transformative Power of Gene Drive-Based Technologies SECTION II MOSQUITO
GENETIC MANIPULATION FOR MALARIA 2. Transgenesis and Paratransgenesis for
the Control of Malaria 3. Gene Drives for Anopheles Mosquitoes 4. Gene
Drive Applications for Malaria Control SECTION III GENE DRIVE MOSQUITO
TRIALS 5. Large Cage Trials of Gene Drive Mosquitoes: Does Size Matter? 6.
Field Trial Site Selection for Mosquitoes with Gene Drive: Geographic,
Ecological, and Population Genetic Considerations 7. Modeling Priorities as
Gene Drive Mosquito Projects Transition from Lab to Field SECTION IV RISK
ASSESSMENT AND COMMUNITY ENGAGEMENT 8. Probabilistic Ecological Risk
Assessment: An Overview of the Process 9. Community Engagement and Mosquito
Gene Drives SECTION V POLICY, REGULATORY, AND ETHICAL CONSIDERATIONS 10.
Review of International Regulatory Instruments and Processes 11. Gene Drive
Mosquitoes: Ethical and Political Considerations