Mouse Phenotypes: Generation and Analysis of Mutants, Second Edition: A Laboratory Manual - Papaioannou, Virginia E; Behringer, Richard R
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This book provides a road map for such analysis. Advice and practical guidance are provided, starting with the planning stages of gene targeting, CRISPR-Cas gene editing, or mutagenesis experiments, through the complete analysis of complex phenotypes, including tips on breeding strategies, studying dominant mutations, and characterizing a mutant mouse with no apparent phenotypic abnormalities.

Produktbeschreibung
This book provides a road map for such analysis. Advice and practical guidance are provided, starting with the planning stages of gene targeting, CRISPR-Cas gene editing, or mutagenesis experiments, through the complete analysis of complex phenotypes, including tips on breeding strategies, studying dominant mutations, and characterizing a mutant mouse with no apparent phenotypic abnormalities.
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Autorenporträt
Virginia E. Papaioannou is a Special Lecturer in Genetics and Development and Professor Emerita of Genetics and Development at Columbia University