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We are glad to introduce this book to all of you. The book contains mucin histochemistry of the colon in normal and malignant lesions. In the present study, combination of special stains such as P.A.S. Diastase, P.A.S.- Phenyl hydrazine, Alcian Blue-P.A.S., Aldehyde fuchsin-Alcian blue were used to simultaneously assess the proportions of various mucin types in the epithelium of colon and rectum examined. The present study has been carried out to find out any variation present in mucosubstances in normal and malignant lesions of the colon. Mucin histochemistry can effectively determine the mucin profile of colorectal adenocarcinoma. Mucin content and type of mucin present can be regarded as important prognostic indicator and early diagnosis may help in reducing mortality regarding colorectal tumors. Mucin histochemistry may provide a valuable and cost-effective tool for the diagnostic histopathology and for the researchers in histology.