Theodore R Holford

Multivariate Methods in Epidemiology

• Gebundenes Buch

Produktbeschreibung

The basis for much of medical public health practice comes from epidemiological research. This text describes current statistical tools that are used to analyze the association between possible risk factors and the actual risk of disease. Beginning with a broad conceptual framework on the disease process, it describes commonly used techniques for analyzing proportions and disease rates. These are then extended to model fitting, and the common threads of logic that bind the two analytic strategies together are revealed. Each chapter provides a descriptive rationale for the method, a worked example using data from a published study, and an exercise that allows the reader to practice the technique. Each chapter also includes an appendix that provides further details on the theoretical underpinnings of the method. Among the topics covered are Mantel-Haenszel methods, rates, survival analysis, logistic regression, and generalized linear models. Methods for incorporating aspects of study design, such as matching, into the analysis are discussed, and guidance is given for determining the power or the sample size requirements of a study. This text will give readers a foundation in applied statistics and the concepts of model fitting to develop skills in the analysis of epidemiological data.

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Produktdetails

• Verlag: Oxford University Press
• Seitenzahl: 440
• Erscheinungstermin: 30. Mai 2002
• Englisch
• Abmessung: 239mm x 165mm x 32mm
• Gewicht: 762g
• ISBN-13: 9780195124408
• ISBN-10: 0195124405
• Artikelnr.: 22155498

Inhaltsangabe

Part I Concept and Definitions
1: Associations Between Exposure and Disease
2: Models for Disease
Part II Non-regression Methods
3: Analysis of Proportions
4: Analysis of Rates
5: Analysis of Time to Failure
Part III Regression Methods
6: Regression Models for Proprtions
7: Defining Regressor Variables
8: Parametric Models for Hazard Functions
9: Proportional Hazards Regression
Part IV Study Design and New Directions
10: Analysis of Matched Studies
11: Power and Sample Size Requirements
12: Extending Regression Models
Appendix 1 Theory on Models for Disease
Appendix 2 Theory on the Analysis of Proportions
Appendix 3 Theory of Analysis Rates
Appendix 4 Theory on Analysis of Time to Failure
Appendix 5 Theory on Regression Models for Proportions
Appendix 6 Theory on Parametric Models for Hazard Function
Appendix 7 Theory on Analysis of Matched Studies