NADH Dehydrogenase Alpha 1

Herausgegeben:Surhone, Lambert M.; Timpledon, Miriam T.; Marseken, Susan F.

• Broschiertes Buch

Produktbeschreibung

High Quality Content by WIKIPEDIA articles! High Quality Content by WIKIPEDIA articles! NADH dehydrogenase 1 alpha subcomplex subunit 1 is an enzyme that in humans is encoded by the NDUFA1 gene. The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participatein that function.

Produktdetails

• Verlag: Betascript Publishing
• Seitenzahl: 132
• Englisch
• ISBN-13: 9786131151828
• ISBN-10: 6131151822
• Artikelnr.: 29970340