Co-authored by Nobel Laureatte, E.J. Corey, this book builds on the first volume on this topic by presenting a comprehensive treatise on name reactions in heterocyclic chemistry. Primary topics include updates to the first volume on the new and/or expanded reactions in three and four-membered heterocycles, five-membered heterocycles, six-membered heterocycles. Each section includes a description of the reaction, the historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and references to the current primary literature.…mehr
Co-authored by Nobel Laureatte, E.J. Corey, this book builds on the first volume on this topic by presenting a comprehensive treatise on name reactions in heterocyclic chemistry. Primary topics include updates to the first volume on the new and/or expanded reactions in three and four-membered heterocycles, five-membered heterocycles, six-membered heterocycles. Each section includes a description of the reaction, the historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and references to the current primary literature.
Jie Jack Li is a Chemist at Bristol-Myers Squibb Company. He has authored or edited various books, including the first volume of Name Reactions in Heterocyclic Chemistry, Name Reactions for Functional Group Transformations, Name Reactions for Carbocyclic Ring Formations, and several others, all published by Wiley.
Inhaltsangabe
Foreword. Preface. Contributing Authors. PART 1 THREE- AND FOUR-MEMBERED HETEROCYCLES. Chapter 1 Aziridines and Epoxides. 1.1 Blum Aziridine Synthesis. 1.2 Gabriel-Heine Aziridine Isomerization. 1.3 Shi Epoxidation. PART 2 FIVE-MEMBERED HETEROCYCLES. Chapter 2 Pyrroles and Pyrrolidines. 2.1 Clauson-Kass Pyrrole Synthesis. 2.2 Houben-Hoech Acylation of Pyrroles. 2.3 Overman Pyrrolidine Synthesis. 2.4 Trofimov Synthesis of Pyrroles. Chapter 3 Indoles. 3.1 Bischler-Möhlau Indole Synthesis. 3.2 Borsche-Drechsel Cyclization. 3.3 Buchwald-Hartwig Indole Synthesis. 3.4 Cadogan-Sundberg Indole Synthesis. 3.5 Fukuyama Indole Synthesis. 3.6 Gassman Oxindole Synthesis. 3.7 Larock Indole Synthesis. 3.8 Matinet Dioxindole Synthesis. 3.9 Mori-Ban Indole Synthesis. 3.10 Sandmeyer Isatin Synthesis. 3.11 Sommelet-Hauser Rearrangement. 3.12 Stollé Oxindole Synthesis. Chapter 4 Furans and Oxazoles. 4.1 Nierenstein Reaction. 4.2 Davidson Oxazole Synthesis. 4.3 Fischer Oxazole Synthesis. 4.4 Japp Oxazole Synthesis. 4.5 Schöllkopf Oxazole Synthesis. Chapter 5 Other Five-Membered Heterocycles. 5.1 Bamberger Imidazole Cleavage. 5.2 Dimroth Triazole Synthesis. 5.3 Finnegan Tetrazole Synthesis. 5.4 Hantsch Thiazole Synthesis. 5.5 Huisgen Tetrazole Rearrangement. 5.6 Knorr Pyrazole Synthesis. 5.7 Pechmann Pyrazole Synthesis. PART 3 SIX-MEMBERED HETEROCYCLES. Chapter 6 Pyridines. 6.1 Baeyer Pyridine Synthesis. 6.2 Katrizky Reaction. Chapter 7 Quinolines and Isoquinolines. 7.1 Betti reaction. 7.2 Bernthsen Acridine Synthesis. 7.3 Lehmstedt-Tanasescu Reaction. 7.4 Niementowski Quinoline Synthesis. 7.5 Povarov Reaction. Chapter 8 Six-Membered Heterocycles. 8.1 Balaban-Nenitzescu-Praill Reaction. 8.2 Borsche Cinnoline Synthesis. 8.3 Gutknecht Pyrazine Synthesis. 8.4 Niementowski Quinazoline Synthesis. 8.5 Pechmann Coumarin Synthesis. 8.6 Robinson-Schöpf Condensation. 8.7 Simonis Chromone Cyclization. 8.8 Wesseley-Moser Rearrangement. 8.9 Widman-Stoermer Cinnoline Synthesis. 8.10 Wichterle Reaction. Chapter 9 Miscellaneous Name Reactions. 9.1 ANRORC Mechanism. 9.2 Boulton-Katritzky Rearrangement. 9.3 Chichibabin Amination Reaction. 9.4 Dimroth Rearrangement. 9.5 Hantzsch Synthesis. 9.6 Ortoleva-King Reaction. Appendices. Appendix 1, Table of Contents for Volume 1: Name Reactions in Heterocyclic Chemistry. Appendix 2, Table of Contents for Volume 2: Name Reactions for Functional Group Transformations. Appendix 3, Table of Contents for Volume 3: Name Reactions for Homologations-I. Appendix 4, Table of Contents for Volume 4: Name Reactions for Homologations-II. Appendix 5, Table of Contents for Volume 5: Name Reactions for Ring Formations.
