The up-to-DATE guide to name reactions in heterocyclic chemistry Name Reactions in Heterocyclic Chemistry II presents a comprehensive treatise on name reactions in heterocyclic chemistry, one of the most exciting?and important?fields within organic chemistry today. The book not only covers fresh ground, but also provides extensive information on new and/or expanded reactions in: * Three- and four-membered heterocycles * Five-membered heterocycles (pyrroles and pyrrolidines, indoles, furans, thiophenes, and oxazoles) * Six-membered heterocycles, including pyridines, quinolines, and…mehr
The up-to-DATE guide to name reactions in heterocyclic chemistry Name Reactions in Heterocyclic Chemistry II presents a comprehensive treatise on name reactions in heterocyclic chemistry, one of the most exciting?and important?fields within organic chemistry today. The book not only covers fresh ground, but also provides extensive information on new and/or expanded reactions in: * Three- and four-membered heterocycles * Five-membered heterocycles (pyrroles and pyrrolidines, indoles, furans, thiophenes, and oxazoles) * Six-membered heterocycles, including pyridines, quinolines, and isoquinolines Featuring contributions from the leading authorities in heterocyclic chemistry. Each section includes a description of the given reaction, as well as the relevant historical perspective, mechanism, variations and improvements, synthetic utilities, experimental details, and references to the current primary literature. The reactions covered in Name Reactions in Heterocyclic Chemistry have been widely adopted in all areas of organic synthesis, from the medicinal/pharmaceutical field, to agriculture, to fine chemicals, and the book brings the most cutting-edge knowledge to practicing synthetic chemists and students, along with the tools needed to synthesize new and useful molecules.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Jie Jack Li is a Chemist at Bristol-Myers Squibb Company. He has authored or edited various books, including the first volume of Name Reactions in Heterocyclic Chemistry, Name Reactions for Functional Group Transformations, Name Reactions for Carbocyclic Ring Formations, and several others, all published by Wiley.
Inhaltsangabe
Foreword viii Preface ix Contributing Authors xi Part 1 Three- and Four-Membered Heterocycles 1 Chapter 1 Aziridines and Epoxides 1 1.1 Blum Aziridine Synthesis 2 1.2 Gabriel-Heine Aziridine Isomerization 11 1.3 Shi Epoxidation 21 Part 2 Five-Membered Heterocycles 41 Chapter 2 Pyrroles and Pyrrolidines 41 2.1 Clauson-Kass Pyrrole Synthesis 42 2.2 Houben-Hoesch Acylation of Pyrroles 53 2.3 Overman Pyrrolidine Synthesis 60 2.4 Trofimov Synthesis of Pyrroles 72 Chapter 3 Indoles 83 3.1 Bischler-Möhlau Indole Synthesis 84 3.2 Borsche-Drechsel Cyclization 91 3.3 Buchwald-Hartwig Indole Synthesis 102 3 .4 Cadogan-Sundberg Indole Synthesis 112 3.5 Fukuyama Indole Synthesis 125 3.6 Gassman Oxindole Synthesis 133 3.7 Larock Indole Synthesis 143 3.8 Matinet Dioxindole Reaction 167 3.9 Mori-Ban Indole Synthesis 175 3.10 Sandmeyer Isatin Synthesis 187 3.11 Sommelet-Hauser Rearrangement 197 3.12 Stolle Oxindole Synthesis 207 Chapter 4 Furans and Ox azoles 213 4.1 Nierenstein Reaction 214 4.2 Davidson Oxazole Synthesis 221 4.3 Fischer Oxazole Synthesis 225 4.4 Japp Oxazole Synthesis 233 4.5 Schhllkopf Oxazole Synthesis 242 Chapter 5 Other Five-Mem be red Heterocycles 259 5. L Bamberger Imidazole Cleavage 260 5.2 Dimroth Triazole Synthesis 269 5.3 Finnegan Tetrazole Synthesis 278 5.4 Hantzsch Thiazole Synthesis 299 5.5 Huisgen Tetrazole Rearrangement 309 5.6 Knorr Pyrazole Synthesis 317 5.7 Pechmann Pyrazole Synthesis 327 Part 3 Six-Membered Heterocycles 337 Chapter 6 Pyridincs 337 6.1 Baeyer Pyridine Synthesis 338 6.2 Katrizky Pyridine Synthesis 347 Chapter 7 Quinolines and Isoquinolines 351 7.1 Betti Reaction 352 7.2 Bemthsen Acridine Synthesis 360 7.3 Lehmstedt-Tanasescu Reaction 368 7.4 Niementowski Quinoline Synthesis 376 7.5 Povarov Reaction 385 Chapter 8 Six-Membered Heterocycles 401 8.1 Balaban-Nenitzescu-Praill Reaction 402 8.2 Borsche Cinnoline Synthesis 420 8.3 Gutknecht Pyrazine Synthesis 430 8.4 Niementowski Quinazoline Synthesis 440 8.5 Pechmann Coumarin Synthesis 454 8.6 Robin son-Schöpf Condensation 470 8.7 Simonis Chromone Cyclization 477 8.8 Wesseley-Moser Rearrangement 487 8.9 Widman-Stoermer Cinnoline Synthesis 493 8.10 Wichterle Reaction 497 Chapter 9 Miscellaneous Name Reactions 515 9.1 ANRORC Mechanism 516 9.2 Boulton-Katritzky Rearrangement 527 9.3 Chichibabin Animation Reaction 539 9.4 Dimroth Rearrangement 554 9.5 Hantzsch Synthesis 591 9.6 Ortolcva-King Reaction 645 Appendixes Appendix 1, Table of Contents for Volume 1: Name Reactions in Heterocyclic Chemistry 651 Appendix 2, Table of Contents for Volume 2: Name Reactions for Functional Group Transformations 655 Appendix 3, Table of Contents for Volume 3: Name Reactions for Hornolegations-I 657 Appendix 4, Table of Contents for Volume 4; Name Reactions for Hornohgations-II 659 Appendix 5, Table of Contents for Volume 5: Name Reactions for Ring Formations 661 Subject Index 663