Name Reactions for Homologation, Part 2

Herausgeber: Li, Jie Jack

• Gebundenes Buch

Produktbeschreibung

"A valuable addition to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help will be impressive and of great benefit to humankind." --From the Foreword by E. J. Corey, Nobel Prize Laureate An invaluable guide to name reactions and reagents for homologations Name Reactions for Homologations, Part II of Wiley's Comprehensive Name Reactions series comprises a comprehensive treatise on name reactions for homologations. With contributions from world-recognized authorities in the field, this reference offers an up-to-date, concise compilation of the most commonly used and widely known name reactions and reagents. Part II discusses Rearrangements, Asymmetric C-C Bond Formation, and Miscellaneous Homologation Reactions. Arranged alphabetically by name reactions, the listing provides: * Description of the reaction * Historical perspective * A mechanism for the reaction * Variations and improvements on the reaction * Synthetic utilities of the reaction * Experimental details * References to the current primary literature Armed with this invaluable resource, both students and professionals will have at their fingertips a comprehensive guide to important mechanisms and phenomena in homologation.

Produktdetails

• Verlag: Wiley
• Seitenzahl: 872
• Erscheinungstermin: 1. April 2009
• Englisch
• Abmessung: 236mm x 193mm x 48mm
• Gewicht: 1597g
• ISBN-13: 9780470464984
• ISBN-10: 0470464984
• Artikelnr.: 26551391

Autorenporträt

Jie Jack Li is a chemist at Bristol-Myers Squibb Company. He received his BS from Nanjing University and his PhD in organic chemistry at Indiana University. Dr. Li completed a postdoctoral fellowship at MIT. He is coauthor of various books, including Name Reactions in Heterocyclic Chemistry, Contemporary Drug Synthesis, Name Reactions for Functional Group Transformations, Name Reactions for Homologations, Parts I and II, Name Reactions on Ring Formations, and The Art of Drug Synthesis, all published by Wiley.

Inhaltsangabe

Foreword.

Preface.

Contributing Authors.

Chapter 1: Rearrangements.

Section 1.1 Concerted rearrangement.

Section 1.2 Cationic rearrangement.

Section 1.3 Anionic rearrangement.

Chapter 2: Asymmetric CC bond formation.

2.1 Evans aldol reaction.

2.2 Hajos-Wiechert reaction.

2.3 Keck stereoselective allylation.

2.4 Roush allylboronation.

Chapter 3: Miscellaneous homologation reactions.

3.1 Bamford-Stevens reaction.

3.2 Mannich reaction.

3.3 Mitsunobu reaction.

3.4 Parham cyclization.

3.5 Passerini reaction.

3.6 Ugi reaction.

Appendixes.

Appendix 1, Table of Contents for Volume 1: Name Reactions inHeterocyclic Chemistry.

Appendix 2, Table of Contents for Volume 2: Name Reactions forFunctional Group Transformations.

Appendix 3, Table of Contents for Volume 3: Name Reactions forHomologations-I.

Appendix 4, Table of Contents for Volume 5: Name Reactions forRing Formations.

Appendix 5, Table of Contents for Volume 6: Name Reactions inHeterocyclic Chemistry-II.

Subject index.

Rezensionen

"Jack Li and his illustrious team of chemists have done it again.It is hard to imagine how one could organize and categorize a topicso broad as "homologation" reactions. These are some of the breadand butter transforms of organic chemistry ? reactions that arefundamentally important to the practice of chemical synthesis. Thistwo book series is masterfully organized and easy to use both as areference work for the classroom and a springboard forpractitioners to rapidly apply these reactions in the laboratory.The extensive coverage of these critical reactions, including ahistorical perspective, mechanism, synthetic utility, and actualexperimental details will ensure that these books will be on theshelf of every serious organic chemist for years to come."

--Phil S. Baran, The Scripps Research Institute