Environment infectious microrganisms are numerous. Continuous research of new additives to restrain and to inhibit their harmful effect to humans must always be attended to. The current work is a serious attempt to restrain familiar strains of serious microrganisms within epoxy and emulsion acrylic paints using more enivironmental safer, effective and and long action additives. Coating and in-can effectiveness were attended in addition to the identification of the additives chemical structure, thermal stability and microbilogical aspects revealence and compatibility.