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This book provides a comprehensive overview of the synthesis, characterization and biological evaluation of new nanoclay doped polyvinyl chloride (PVC) and polyester blend composite films. The book discusses the preparation of nanoclay doped composite films using various techniques such as solvent casting, solution blending and melt mixing. The physicochemical properties of these composite films were studied using various analytical techniques such as X-ray diffraction, thermogravimetric analysis, differential scanning calorimetry and scanning electron microscopy. The biological evaluation of these nanoclay doped composite films was carried out using various techniques such as cytotoxicity assays, bacterial adhesion assays and cell proliferation assays. The results of these biological evaluations indicate that the nanoclay doped composite films have potential applications in the field of medical implants, wound healing, drug delivery systems and tissue engineering. This book provides a valuable resource for researchers and professionals in the field of materials science, biomaterials and nanotechnology, who are interested in the development of new composite materials for biological applications. It is also suitable for graduate students and advanced undergraduate students who are interested in the synthesis, characterization and biological evaluation of new composite materials.