This work focuses on the formulation of oil-in-water nanoemulsions, their physicochemical and structural properties, stability mechanisms, destabilization phenomena and their industrial application. In fact, nanoemulsions are the type of transparent or translucent emulsion with droplet sizes ranging from 20 to 500 nm. The stability and application of nanoemulsions depend on the droplet and physicochemical characteristics. The droplet characteristics are studied through droplet size, droplet composition, droplet concentration, zeta potential, polydispersity and interfacial tension. The physicochemical properties are studied through their optical property, rheological property, gravitational separation, droplet aggregation, Ostwald ripening and chemical stability. Emulsifiers and surfactants contribute to the emulsification process and are selected according to the requirements of the emulsification methods and the expected quality of the nanoemulsion. Nanoemulsions have many applications in the food industry, pharmaceutical industry, ...