Fabrication of biogenic metal nanoparticles is developing area of Nano biotechnology which has economic and potentially eco-friendly advantages over conventional chemical and physical synthesis methods. Once nanomaterial¿s (NMs) enters the tissues of organisms or are transported across cell membranes, toxicity is likely to occur principally through one or a combination of four mechanisms. Potential application of Au NPs in biomedicine this is increasing questions about possible risks for human health and environment. In general, gold nanoparticles are recognized as being as nontoxic carriers for drug and gene delivery application, This study targets Researcher, Scientist and Pharmacist in the Fields Nano biotechnology, Pharmaceutical and Chemical Engineering, Drugs Developing, Medicinal Plants, Pharmaceutical Nano Toxicology.