Nanotechnology has emerged as a groundbreaking frontier in the field of periodontics, at the nanoscale level, materials exhibit unique properties that can be leveraged for targeted therapeutic interventions. In periodontal care, this translates to precision and effectiveness previously unseen. Nanotechnology represents a paradigm shift in periodontics and learning about nanotechnology in periodontics is crucial for its potential to revolutionize diagnosis and treatment. Nanomaterials enable precise diagnostics, targeted drug delivery, and antimicrobial solutions, improving therapeutic efficacy while minimizing side effects. In regenerative medicine, nanotechnology promotes tissue regeneration. Staying informed ensures practitioners can leverage these advancements for personalized, effective, and minimally invasive periodontal care. This book highlights various advancements seen over the years in nanotechnology relating to periodontics which will help the practitioner gain sound knowledge to further research and implement in practice.