Nanotechnology is the science and engineering involved in the design, synthesis, characterization, and application of materials and devices whose smallest functional organization in at least one dimension is on the nanometer scale or one billionth of a meter. The potential benefit of nanotechnology is its ability to exploit the atomic and molecular properties of materials and to develop newer materials with better properties. Growing interest in the future medical applications of nanotechnology is leading to the emergence of a new field called Nanomedicine. Research and development in nanomaterials and nanodevices were identified as the development of technology to satisfy the biological and medical applications. The main purpose is, therefore, to provide an early glimpse of nanodental applications and to illustrate their potentially far-reaching impact on clinical dental practice.