Nanomaterials have been playing a significant role in basic scientific innovation and clinical technological change of prosthodontics. With emerging technologies and upcoming of new nanotechnology in the field of dentistry there is improvement in all aspects of diagnostics, therapeutics and cosmetic dentistry. Nanotechnology will make healthcare more effective and affordable. In the next coming years, molecular technology will be destined to become core technology underlying all of the 21st century of medicine and dentistry.