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Various compounds are synthesized and tested to sensitize tumor cells to radiation. Among the various nitro-heterocyclic hypoxic cell radiosensitizers,Sanazole commonly referred as AK2123 has been shown to have less toxicity in normal cells and have selective toxicity for hypoxic cells.The present work focuses on the radiomodifying property of sanazole and its nanoparticles complex in Dalton's Lymphoma Ascites (DLA)cells.These data suggest that this approach could be used for tumors raising the hope of targeted therapeutic agents with the ability to interfere specifically with tumor cell growth.…mehr

Produktbeschreibung
Various compounds are synthesized and tested to sensitize tumor cells to radiation. Among the various nitro-heterocyclic hypoxic cell radiosensitizers,Sanazole commonly referred as AK2123 has been shown to have less toxicity in normal cells and have selective toxicity for hypoxic cells.The present work focuses on the radiomodifying property of sanazole and its nanoparticles complex in Dalton's Lymphoma Ascites (DLA)cells.These data suggest that this approach could be used for tumors raising the hope of targeted therapeutic agents with the ability to interfere specifically with tumor cell growth.
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Autorenporträt
Viji.M.O.,Ph.D Scholar in Biotechnology,Avinashilingam Deemed University,Coimbatore,Tamilnadu,India.She has completed MSc.MPhil in the same field.She has 5 years of teaching experience and as an external examiner in affiliated Colleges under Calicut University.Many Publications of both National and International Journals in her credit.