This guide covers the current state of knowledge on intrinsic fluorescent biomarkers and highlights advances in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. The book's first section introduces the fundamentals of cellular energy metabolic pathways as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods. The last two sections explore applications in biochemistry, cell biology, and medicine.…mehr
This guide covers the current state of knowledge on intrinsic fluorescent biomarkers and highlights advances in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. The book's first section introduces the fundamentals of cellular energy metabolic pathways as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods. The last two sections explore applications in biochemistry, cell biology, and medicine.
Vladimir V. Ghukasyan is a research assistant professor in the Department of Cell Biology and Physiology and a director of the Confocal and Multiphoton Imaging Facility of the Neuroscience Center at the University of North Carolina at Chapel Hill. He earned a PhD in biology from the Institute of Biotechnology, Yerevan, Armenia, and completed postdoctoral training at the Institute of Biophotonics, Taipei, Taiwan. Ahmed A. Heikal is a professor in the Department of Chemistry and Biochemistry, Swenson College of Science and Engineering at the University of Minnesota Duluth. His research interests in molecular and cellular biophysics were inspired by his work with Watt W. Webb as a postdoctoral associate at Cornell University. Dr. Heikal earned a PhD in applied physics from the California Institute of Technology under the supervision of Nobel Laureate Ahmed H. Zewail.
Inhaltsangabe
Biochemical, Biological, and Biophysical Background. Autofluorescence Imaging Techniques: Fundamentals and Applications. Natural Biomarkers for Biochemical and Biological Studies. Autofluorescence as a Diagnostic Tool in Medicine and Health. Index.
Biochemical, Biological, and Biophysical Background. Autofluorescence Imaging Techniques: Fundamentals and Applications. Natural Biomarkers for Biochemical and Biological Studies. Autofluorescence as a Diagnostic Tool in Medicine and Health. Index.
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