Neglected Diseases: Extensive Space for Modern Drug Discovery

Herausgegeben:Botta, Maurizio

• Gebundenes Buch

Produktbeschreibung

Neglected Diseases: Extensive Space for Modern Drug Discovery provides in-depth reviews on the last progresses about neglected tropical diseases research. Topics covered in this volume include Leishmaniasis, Tripanosomiasis, Onchocerciasis and Ebolavirus infections, with insights on the future of the research on them. Part of the volume is devoted to recent contributions this field received from X-Ray crystallography.

Produktdetails

• Annual Reports in Medicinal Chemistry Volume 51
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: S0065-7743(18)X0002-5
• Englisch
• Abmessung: 14mm x 152mm x 229mm
• Gewicht: 520g
• ISBN-13: 9780128151433
• Artikelnr.: 53779322

Autorenporträt

Maurizio Botta obtained a degree with laude in Chemistry at University of Rome in 1974. In November 1977 he got the PhD at the University of New Brunswick. He has been researcher in Organic Chemistry at University of Rome (1981-1987). From November 2009 to October 2012 he was Dean of the Faculty of Pharmacy at the University of Siena. From January 2008 he is Adjunct Professor in Temple University College of Science and Technology, Philadelphia (USA) and, since 2000, he is Full Professor of Medicinal Chemistry at the Department of Biotechnology Chemistry and Pharmacy of University of Siena. Author of more than 500 papers, 26 patents, and more than 450 proceedings at congresses. EU Expert for reviewing projects belonging to the TMR research program and in the panel "Quality of Life?. Member of the Editorial Board of ChemMedChem, JMedChem and JChemInfoModel, Associate Editor for MedChemLetters. Member of the Committees of several scientific Schools and Meetings. Co-founder of two spi

n-off (MoLiRom, LeadDiscoverySiena).

Inhaltsangabe

1. Targeting Human Onchocerciasis: Recent Advances Beyond Ivermectin Stefano Sainas, Franco Dosio, D. Boschi and M.L. Lolli 2. Scaffolds and Biological Targets Avenue to Fight Against Drug Resistance in Leishmaniasis Chiara Borsari, Antonio Quotadamo, Stefania Ferrari, A. Venturelli, Anabela Cordeiro, Nuno Santarem and Maria Paola Costi 3. Drugs and Drug Resistance in African and American Trypanosomiasis Jaime Franco, Laura Scarone and Marcelo A. Comini 4. Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules Elisa Fanunza, Aldo Frau, Angela Corona and Enzo Tramontano 5. X-Ray Crystallography Contributions to Drug-Discovery Against Parasite Infections Cecilia Pozzi, Giusy Tassone and Stefano Mangani