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High Quality Content by WIKIPEDIA articles! Neo-Darwinism is a term used today to describe the 'modern synthesis' of Darwinian evolution by natural selection with Mendelian genetics, the latter of which Darwin himself had been unaware, but which entails that the mechanism of inheritance in evolution involves the digital, particulate entities known as genes, rather than the 'blending process' of pre-Mendelian evolutionary science. Neo-Darwinism also separates Darwin's ideas of natural selection from his hypothesis of Pangenesis as a Lamarckian source of variation involving blending inheritance.The term was first used by George Romanes in 1895 to refer to the idea that evolution occurs solely through natural selection, as proposed by Alfred Russel Wallace and August Weismann, in other words, without any mechanism involving the inheritance of acquired characteristics resulting from use or disuse.