The new edition of this textbook integrates the history, epidemiology, pathology, pathophysiology, therapeutics, and supportive care of modern neoplastic hematopathology. Now in its sixth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. The textbook is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia, including chronic leukemias and related disorders, acute leukemias, myeloma and related disorders, and…mehr
The new edition of this textbook integrates the history, epidemiology, pathology, pathophysiology, therapeutics, and supportive care of modern neoplastic hematopathology. Now in its sixth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. The textbook is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia, including chronic leukemias and related disorders, acute leukemias, myeloma and related disorders, and lymphomas, and the fifth section covering a variety of topics in supportive care. Chapters are presented in an accessible and easy-to-read layout, providing updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. Neoplastic Diseases of the Blood, Sixth Edition is an authoritative and indispensable resource for students, trainees, and clinicians, sure to distinguish itself as the definitive reference on this subject.
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Autorenporträt
Peter H. Wiernik, MD, Doctor HC Cancer Research Foundation, Chappaqua, NY, USA Janice P. Dutcher, MDCancer Research Foundation, Chappaqua, NY, USA Morie A. Gertz, MDMayo Clinic, Department of Hematology, Rochester, MN, USA
Inhaltsangabe
A History of the Chronic Leukemias.- Epidemiology and Etiology of Chronic Myeloid Leukemia.- Pathology of the Chronic Myeloid Leukemias.- Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia.- Diagnosis and Treatment of Chronic Myeloid Leukemia.- Etiology and Epidemiology of CLL.- Morphology and Immunophenotype of CLL.- The Genomic and Epigenomic Landscape of Chronic Lymphocytic Leukemia.- Treatment of Chronic Lymphocytic Leukemia and Related Disorders.- Hairy Cell Leukemia.- History of Acute Leukemia.- The Etiology of Acute Leukemia.- Epidemiology and Hereditary Aspects of Acute Leukemia.- Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations.- Immunobiology of Acute Leukemia.- Cytogenetics of Acute Leukemia.- Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia.- Diagnosis and Treatment of Adult Acute Lymphocytic Leukemia.- Diagnosis and Treatment of Acute Myeloid Leukemia in Children.- Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other than Acute Promyelocytic Leukemia.- Acute Promyelocytic Leukemia.- Therapy-Related Acute Myelogenous Leukemia.- The Myelodysplastic Syndromes.- History of Multiple Myeloma.- Monoclonal Gammopathy of Undetermined Significance.- Smoldering Multiple Myeloma.- Newly Diagnosed Multiple Myeloma in Frail Patients.- Newly Diagnosed Multiple Myeloma in Transplant Eligible Patients.- Role of Hematopoietic Cell Transplantation for Myeloma.- Solitary Plasmacytomas and Soft-Tissue Involvement in Multiple Myeloma.- Supportive Care in Multiple Myeloma.- POEMS Syndrome.- Waldenstrom's Macroglobulinemia.- Plasma Cell Leukemia.- Prognosis of Myeloma/Genetics of Myeloma.- Immunoglobulin Light Chain Amyloidosis (AL).- Historical Landmarks in an Understanding of the Lymphomas.- Genetics in Lymphomagenesis.- Epidemiology and Hereditary Aspects of Hodgkin and Non-Hodgkin Lymphomas.- Pathology of Non-Hodgkin and Hodgkin Lymphomas.- Immunology of the Lymphomas.- Cytogenetics of Lymphomas.- Diagnosis and Treatment of Hodgkin Lymphoma.- Radiotherapeutic Management of Lymphomas.- Diagnosis and Treatment of Non-Hodgkin's Lymphoma of Adults.- Non-Hodgkin Lymphoma of Childhood.- Lymphoma in Other Diseases.- Supportive Care for Patients with Leukemia: A Historical Perspective.- Prevention of Infections in Patients with Hematological Malignancies.- Evaluation and Management of Bacterial and Fungal Infections in Patients with a Hematological Malignancy: A 2016 Update.- Viral Infections in Patients with Hematological Malignancies.- Therapeutic Cytapheresis, Plasmapheresis, and Plasma Exchange in Neoplastic Diseases of the Blood.- Red Cell Transfusions in Patients with Hematologic Malignancies.- Platelet and Granulocyte Transition.- Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications.- HLA Typing in Support of Hematopoietic Cell Transplantation from Unrelated Donors.- Special Care of Blood and Marrow Hematopoietic Cell Transplant Recipient.- HematopoieticGrowth Factors in the Supportive Care and Treatment of Patients with Hematologic Neoplasms.- Bleeding and Thrombosis in Hematologic Neoplasia.- Psychological Aspects of Hematological Neoplasms.
A History of the Chronic Leukemias.- Epidemiology and Etiology of Chronic Myeloid Leukemia.- Pathology of the Chronic Myeloid Leukemias.- Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia.- Diagnosis and Treatment of Chronic Myeloid Leukemia.- Etiology and Epidemiology of CLL.- Morphology and Immunophenotype of CLL.- The Genomic and Epigenomic Landscape of Chronic Lymphocytic Leukemia.- Treatment of Chronic Lymphocytic Leukemia and Related Disorders.- Hairy Cell Leukemia.- History of Acute Leukemia.- The Etiology of Acute Leukemia.- Epidemiology and Hereditary Aspects of Acute Leukemia.- Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations.- Immunobiology of Acute Leukemia.- Cytogenetics of Acute Leukemia.- Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia.- Diagnosis and Treatment of Adult Acute Lymphocytic Leukemia.- Diagnosis and Treatment of Acute Myeloid Leukemia in Children.- Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other than Acute Promyelocytic Leukemia.- Acute Promyelocytic Leukemia.- Therapy-Related Acute Myelogenous Leukemia.- The Myelodysplastic Syndromes.- History of Multiple Myeloma.- Monoclonal Gammopathy of Undetermined Significance.- Smoldering Multiple Myeloma.- Newly Diagnosed Multiple Myeloma in Frail Patients.- Newly Diagnosed Multiple Myeloma in Transplant Eligible Patients.- Role of Hematopoietic Cell Transplantation for Myeloma.- Solitary Plasmacytomas and Soft-Tissue Involvement in Multiple Myeloma.- Supportive Care in Multiple Myeloma.- POEMS Syndrome.- Waldenstrom's Macroglobulinemia.- Plasma Cell Leukemia.- Prognosis of Myeloma/Genetics of Myeloma.- Immunoglobulin Light Chain Amyloidosis (AL).- Historical Landmarks in an Understanding of the Lymphomas.- Genetics in Lymphomagenesis.- Epidemiology and Hereditary Aspects of Hodgkin and Non-Hodgkin Lymphomas.- Pathology of Non-Hodgkin and Hodgkin Lymphomas.- Immunology of the Lymphomas.- Cytogenetics of Lymphomas.- Diagnosis and Treatment of Hodgkin Lymphoma.- Radiotherapeutic Management of Lymphomas.- Diagnosis and Treatment of Non-Hodgkin's Lymphoma of Adults.- Non-Hodgkin Lymphoma of Childhood.- Lymphoma in Other Diseases.- Supportive Care for Patients with Leukemia: A Historical Perspective.- Prevention of Infections in Patients with Hematological Malignancies.- Evaluation and Management of Bacterial and Fungal Infections in Patients with a Hematological Malignancy: A 2016 Update.- Viral Infections in Patients with Hematological Malignancies.- Therapeutic Cytapheresis, Plasmapheresis, and Plasma Exchange in Neoplastic Diseases of the Blood.- Red Cell Transfusions in Patients with Hematologic Malignancies.- Platelet and Granulocyte Transition.- Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications.- HLA Typing in Support of Hematopoietic Cell Transplantation from Unrelated Donors.- Special Care of Blood and Marrow Hematopoietic Cell Transplant Recipient.- HematopoieticGrowth Factors in the Supportive Care and Treatment of Patients with Hematologic Neoplasms.- Bleeding and Thrombosis in Hematologic Neoplasia.- Psychological Aspects of Hematological Neoplasms.
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