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Iodinated contrast nephropathy (ICN) is increasingly encountered in interventional cardiology. It is the third most common cause of acute renal failure in hospitals, after functional renal failure and drug-induced causes. It is a formidable complication that can hamper clinical prognosis and make subsequent management of patients more difficult. Several factors can predict the occurrence of this entity. The aim of this study is to identify factors predictive of the occurrence of nephropathy associated with iodinated contrast media in cardiology.Methodology: This is a retrospective study of 133 patients investigated by coronary angiography or treated by coronary angioplasty in the cardiology department of Mongi Slim Hospital over a 3-month period between April and June 2023.