The purpose of this research was to generate psycho-pedagogical strategies of conditioned neuro-development oriented to the sport activity of Karate-Do, based on the theories of neuroplasticity, offered by researchers such as Doherty (2023) referred to neuroscience applied to education and sport; also the theory of the zone of proximal development supported among others by Pontón (2020), in addition to the theory of conditioned reflexes provided by researchers such as Polanco (2016) on the impact and evolution of behaviorism. The research is based on an emerging approach of methodological complementarity. The study is quasi-experimental with a pre- and post-test design with control group. The analysis of the information is based on qualitative techniques, using discourse analysis. The complementary epistemological and methodological foundation allowed describing the empirical components and interpreting the theoretical and structural principles of an emerging socio-sports model in Venezuela, by strengthening the organization and participation of children, youth and adults in sports spaces and organizations.