Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimer's Disease

2-volume set
Herausgeber: Kumar, Amit; Singh, Varinder; Sood, Parul

• Broschiertes Buch

Produktbeschreibung

Delves into the potential of nature's pharmacopeia against Alzheimer's. Details the disease and potential therapeutic interventions, pathophysiology, diagnosis, etc. Covers latest strategies for effective Alzheimer's management. Explores nutraceuticals, their mechanisms, and potential integration into Alzheimer's management strategies.

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Produktdetails

• Verlag: Apple Academic Press Inc.
• Seitenzahl: 759
• Erscheinungstermin: 4. April 2025
• Englisch
• Abmessung: 234mm x 156mm
• ISBN-13: 9781774918449
• ISBN-10: 1774918447
• Artikelnr.: 72182582

Autorenporträt

Varinder Singh, PhD, is working as Assistant Professor in the Department of Pharmaceutical Sciences and Technology at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India. His research interests primarily lie in the discovery and development of natural products for therapeutic use. He is well-versed in the fields of natural product chemistry (isolation and characterization of bioactive natural compounds), drug discovery, and pharmacology. He has a strong record of publications in high-impact peer-reviewed journals (39 peer-reviewed publications), with many of his papers cited extensively in the field of natural products. He has one patent granted. He has been awarded with numerous travel grants from government and non-government organizations, including the Alzheimer's Association International, the Indian Department of Science and Technology, Indian Council of Medical Research, and International Brain Research Organization. He earned his PhD (Pharmaceutical Sciences) at Punjabi University, Patiala, Punjab, India. Amit Kumar, PhD, is working as Associate Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. He has 12 years of teaching and research experience and has published more than 20 research articles in international journals. He has to date 371 citations and an h-index of 11. He has filed three patents. His area of research includes neuroprotective drug development and elucidating pathological features of diseases. He has received various awards and grants from the International Brain Research Organization, the Indian Department of Science and Technology (DST)-Science and Engineering Research Board, and the Indian Council of Medical Research. He is a certified trainer of Scientific Medical Writing approved from the Life Sciences Sector Skill Development Council and DST (Govt. of India). He received his graduate, postgraduate, and PhD degrees in Pharmaceutical Sciences from Punjabi University Patiala, Punjab, India. Parul Sood, PhD, is working as an Associate Professor at Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India. She has more than 14 years of professional experience in teaching and research. Her area of specialization and research is exploring herbal plants for the treatment of various neurological disorders including, Alzheimer's disease, as well as pharmacognostical and phytochemical evaluation, and standardization of herbal drugs and herbal drug formulation development. She is a gold medalist in MPharm and GATE as well as GPAT qualified. She has a total of 12 publications in reputed journals and has presented a total of 15 oral/poster presentations at national and international conferences and was awarded third position at two national conferences. She completed her PhD at the Department of Pharmaceutical Sciences, Punjabi University Patiala, Punjab, India.

Inhaltsangabe

VOLUME 1: TARGETING KEY PATHOLOGICAL PATHWAYS PART I: MOLECULAR AND GENETIC
PATHWAYS IN ALZHEIMER'S DISEASE 1. Pathophysiology and Diagnosis of
Alzheimer's Disease: Past and Recent Developments 2. Tangled Connection of
Gut Microbiome and Alzheimer's Disease 3. Epigenetic Modifications in
Alzheimer's Disease 4. Drug-Induced Alzheimer's Disease 5. The Road to Drug
Discovery Targeting Abnormal Proteins: Taking a Glance at Alzheimer's
Treatments Through Rose-Colored Glasses 6. Preclinical Testing Methods for
Evaluation of Potential Anti-Alzheimer's Drugs PART II: NUTRACEUTICALS FOR
THE MANAGEMENT OF ALZHEIMER'S DISEASE 7. Medhya Rasayanas for the
Management of Alzheimer's Disease 8. Management of Alzheimer's Disease in
the Light of Ayurveda 9. Nootropics: Traditional Medicinal Prospective 10.
Ethnopharmacological Approaches for Dementia 11. Role of Diet,
Micronutrients, and Macronutrients in Managing Alzheimer's Disease VOLUME
2: STRATEGIES TO UNLOCK THE BRAIN'S FORTRESS PART I: NUTRACEUTICALS:
HOLISTIC APPROACHES TO ALZHEIMER'S MANAGEMENT 1. Emergent Natural
Antioxidant Therapeutics to Cope with Oxidative Stress in Alzheimer's
Disease 2. Exploring Beta Secretase Inhibitors as the Evergreen Drug Target
for Alzheimer's Disease: Calling Herbal Therapies to the Rescue 3. Role of
Natural Steroidal Phytopharmaceuticals in the Management of Alzheimer's
Disease 4. Potential Role of Terpenes in the Management of Alzheimer's
Disease 5. Anti-Apoptotic Natural Products for the Management of
Alzheimer's Disease 6. Potential Natural Polysaccharides for the Management
of Alzheimer's Disease 7. Neuro-Protective Role of Vitamin D in Alzheimer's
Disease 8. Role of Non-Flavonoidal Agents in Alzheimer's Disease PART II:
RECENT DEVELOPMENTS AND ADVANCEMENTS IN THE DELIVERY OF NUTRACEUTICALS
ACROSS BLOOD-BRAIN-BARRIER 9. Drug Delivery Strategies for Drug Targeting
for Alzheimer's Disease 10. Nanocargos for Efficient Delivery of
Nutraceuticals Across Blood-Brain Barrier 11. Recent Advancement in
Strategies for Delivery of Neuronutraceuticals to the Brain