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In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation…mehr

Produktbeschreibung
In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.
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Autorenporträt
University of Saskatchewan, Canada
Rezensionen
Review of the first edition:
"...will reach a wide audience including basic and clinical neuroscientists. . .fills a significant gap in the literature...provides an excellent starting point, and offers insight into the rapid pace of discovery within a field which influences most aspects of nervous system function."-Nature Medicine

"...fills a significant gap in the literature...provides an excellent starting point..."
-Nature Medicine

"...will be useful to a wide variety of researchers and clinicians, particularly [those] interested in neurodegenerative disorders ..."
-Neurological Research

"...provides a thorough overview of cells and mechanisms of brain inflammation, their role in disease and future therapeutic avenues to overcome it."
-MicrobiologyToday

"...a timely addition that will aid our understanding today."
-Receptors & Signal Transduction