Neuropathology of Aging and Alzheimer’s Disease takes a foundational approach to the topic by offering basic scientific information and the latest advancements in the field. The focus of this reference is on neuropathology and recent advances in tissue characterization in aging, and in Alzheimer’s Disease. Neuropathology has direct relevance to therapeutic constructs and allows for an in-depth understanding of disease pathogenesis. It is a synthesis of the salient issues with respect to pathology, pathogenesis, diagnosis, disease, normal aging, biomarker relevance, and prospects for therapeutic intervention.…mehr
Neuropathology of Aging and Alzheimer’s Disease takes a foundational approach to the topic by offering basic scientific information and the latest advancements in the field. The focus of this reference is on neuropathology and recent advances in tissue characterization in aging, and in Alzheimer’s Disease. Neuropathology has direct relevance to therapeutic constructs and allows for an in-depth understanding of disease pathogenesis. It is a synthesis of the salient issues with respect to pathology, pathogenesis, diagnosis, disease, normal aging, biomarker relevance, and prospects for therapeutic intervention.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Dr. Rudolph J. Castellani is a pathologist in Baltimore, Maryland and is affiliated with multiple hospitals in the area, including¿West Virginia University Hospitals¿and¿Davis Medical Center. He received his medical degree from Wayne State University School of Medicine and has been in practice for more than 20 years. He specializes in Pathology, Neuropathology and Anatomic Pathology. He's published hundreds of articles, and has received ~19 honors and awards.
Inhaltsangabe
1. Alzheimer's disease: A Fortuitous Beginning 2. Alzheimer's First Case 3. Alzheimer's Second Case and the Naming of Alzheimer's Disease 4. Some Early Observations of Alzheimer Contemporaries 5. Early Studies on Senile Dementia and Aging 6. The Human Element 7. The 1920s and 1930s 8. The 1940s to the 1960s 9. Lewy Bodies 10. The Role of Vascular Disease in Alzheimer’s Disease Neuropathology 11. The Rise of the Acronym 12. Age-related Neuronal Tau 13. Aging-related tau astrogliopathy 14. TDP-43 in aging and Alzheimer’s disease 15. Argyrophilic Grain Disease 16. Introduction to the Traumatic Brain Injury-Neurodegenerative Disease Dichotomy 17. Punch Drunk Syndrome: The First 30 Years 18. Pathology Studies from the 1950s and 1960s; the Roberts Study 19. 1970's to 2000's: Transitioning to an Immunohistochemistry-Only Diagnosis 20. The modern CTE era 21. Postmortem of Punch Drunk Boxers and CTE 22. Familial Alzheimer’s disease and Down Syndrome 23. The modern CTE era 24. Application of consensus criteria 25. The Diagnostic Process
1. Alzheimer's disease: A Fortuitous Beginning 2. Alzheimer's First Case 3. Alzheimer's Second Case and the Naming of Alzheimer's Disease 4. Some Early Observations of Alzheimer Contemporaries 5. Early Studies on Senile Dementia and Aging 6. The Human Element 7. The 1920s and 1930s 8. The 1940s to the 1960s 9. Lewy Bodies 10. The Role of Vascular Disease in Alzheimer’s Disease Neuropathology 11. The Rise of the Acronym 12. Age-related Neuronal Tau 13. Aging-related tau astrogliopathy 14. TDP-43 in aging and Alzheimer’s disease 15. Argyrophilic Grain Disease 16. Introduction to the Traumatic Brain Injury-Neurodegenerative Disease Dichotomy 17. Punch Drunk Syndrome: The First 30 Years 18. Pathology Studies from the 1950s and 1960s; the Roberts Study 19. 1970's to 2000's: Transitioning to an Immunohistochemistry-Only Diagnosis 20. The modern CTE era 21. Postmortem of Punch Drunk Boxers and CTE 22. Familial Alzheimer’s disease and Down Syndrome 23. The modern CTE era 24. Application of consensus criteria 25. The Diagnostic Process
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