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Main description:
Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspective and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.
Key - Description of the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode
- Chapters on the different factors affecting the
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Produktbeschreibung
Main description:
Since 1959, International Review of Neurobiology has been a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspective and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.

Key - Description of the mechanisms involved in cell death and the biochemical changes occurring during an ischaemic episode
- Chapters on the different factors affecting the neurodegenerative process and how compounds acting on these systems may lead to novel neuroprotective agents
- Reviews of in vitro and in vivo models of stroke and the activity of putative neuroprotective drugs
- Discussion of the application of pre-clinical data to the clinical problem
- Detailed reviews of both completed clinical trials and those currently underway

Review quote:
"In balance, I recommend this book as a superior volume, whose high 'power-to-weight ratio,' readability, and availability in paperback make it attractive for personal use."
--TRENDS IN NEUROSCIENCES

Table of contents:
R.M.E. Chalmers-Redman, A.D. Fraser, W.Y.H. Ju, J. Wadia, N.A. Tatton, and W.G. Tatton, Mechanisms of Nerve Cell Death: Apoptosis or Necrosis after Cerebral Ischaemia.

T. Kristian and B.K. Siesjo, Changes in Ionic Fluxes during Cerebral Ischaemia.

A.R. Green and A.J. Cross, Techniques for Examining Neuroprotective Drugs in Vivo.

M.P. Goldberg, U. Strasser, L.L. Dugan, Techniques for Examining Neuroprotective Drugs in Vitro.

A.J. Hunter, Calcium Antagonists: Their Role in Neuroprotection.

T.P. Obrenovich, Sodium and Potassium Channel Modulators: Their Role in Neuroprotection.

D.L. Small and A.M. Buchan, NMDA Antagonists: Their Role in Neuroprotection.

R.N. McBurney, Development of the NMDA Ion-Channel Blocker Aptiganel Hydrochloride as a Neuroprotective Agent for Acute CNS Injury.

R. Gill and D. Lodge, The Pharmacology of AMPA Antagonists and their Role in Neuroprotection.

P.D. Lyden, GABA and Neuroprotection.

B.B. Fredholm, Adenosine and Neuroprotection.

N.J. Rothwell, S.A. Loddick, and P. Stroemer, Interleukins and Cerebral Ischaemia.

K. Hensley, J.M. Carney, C.A. Stewart, T. Tabatabaie, Q. Pye, and R.A. Floyd, Nitrone-Based Free Radical Trapsas Neuroprotective Agents in Cerebral Ischaemia and other Pathologies.

T. Dalkara and M.A. Moskowitz, Neurotoxic and Neuroprotective Roles of Nitric Oxide in Cerebral Ischaemia.

N.-G. Wahlgren, A Review of Earlier Clinical Studies on Neuroprotective Agents and Current Approaches.
Subject Index.
Autorenporträt
Alan Cross was at the MRC Clinical Research Centre, London, followed by two years as a lecturer in the Department of Physiology, University of Manchester. In 1980 he became Head of Pharmacology at the Aston Neuroscience Research Unit.